ArticleCureus2025
Anesthetic Management of a Patient With Acute Necrotizing Encephalopathy Type 1.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Acute necrotizing encephalopathy (ANE) is a progressive neurodegenerative condition that often arises after exposure to a variety of viruses and systemic infections, including influenza and SARS-CoV-2. It typically presents with developmental delay, seizures, dysarthria, and ataxia. Acute necrotizing encephalopathy type 1 (ANE1) is recurrent, and familial cases have been associated with mutations in the RAN-binding protein 2 (RanBP2) gene. The disease shares symptomatic and pathological resemblance with mitochondrial metabolic disorders. In this case report, we present the anesthetic management of a seven-year-old boy with ANE1 who underwent total hip reconstruction. Literature on the anesthetic management of such patients is sparse, and we discuss the patient's perioperative anesthetic management, including medications, monitoring, and care, along with a literature review.
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