ArticleThe EMBO journal1985
Sequencing of the chicken non-erythroid spectrin cDNA reveals an internal repetitive structure homologous to the human erythrocyte spectrin.
Article in The EMBO journal, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 32 citations in OpenAlex.
- The two major membrane skeletal proteins (articulins) of Euglena gracilis define a novel class of cytoskeletal proteins.The Journal of cell biology · 1992Article
- The complete sequence of Drosophila alpha-spectrin: conservation of structural domains between alpha-spectrins and alpha-actinin.The Journal of cell biology · 1989Article
- Primary structure of the brain alpha-spectrin.The Journal of cell biology · 1989Article
- Regulation of erythroid cell-specific gene expression during erythropoiesis.The British journal of cancer. Supplement · 1988Review
- Comparison of nonerythroid alpha-spectrin genes reveals strict homology among diverse species.Molecular and cellular biology · 1988Article
- Isolation and characterization of cDNA clones for human erythrocyte beta-spectrin.Proceedings of the National Academy of Sciences of the United States of America · 1987Article
- Cloning of a portion of the chromosomal gene for human erythrocyte alpha-spectrin by using a synthetic gene fragment.Proceedings of the National Academy of Sciences of the United States of America · 1986Article
- Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.Proceedings of the National Academy of Sciences of the United States of America · 1985Article
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Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunological screening of a chicken gizzard cDNA expression library was used to isolate two clones encoding a part of the non-erythroid spectrin-like protein. Clones were identified by immunoblotting of the polypeptides synthesized in Escherichia coli cells transformed with cDNA cloned in the pUC8 plasmid vector using polyclonal rabbit antibodies raised against bovine non-erythroid spectrin. The sequence of an approximately 1.5-kb cDNA insert of one clone was determined. Analysis of the predicted amino acid sequence reveals that, despite differences in immunological cross-reactivity and peptide maps, the chicken non-erythroid and the human erythrocyte spectrins are highly homologous proteins. Like the human erythrocyte spectrin, the chicken smooth muscle spectrin appears also to be constructed from repeated, homologous structures of 106 amino acid residues. This is probably a universal structure motif of spectrins.
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Registered trials
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