Evidence map›Paper›PMID 40291151›Full record

ArticleSAGE open medicine2025

Efficacy and safety of capsaicin 8% patches: The experience of a rheumatology department.

Sylvain Mathieu, Marion Couderc, Marine Beauger, Sandrine Malochet-Guinamand, Marie-Eva Pickering, Martin Soubrier, Anne Tournadre

Abstract read
In one paragraph

Article in SAGE open medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sylvain MathieuRheumatology Department, Gabriel Montpied Teachin Hospital, Clermont-Ferrand, France.ORCID https://orcid.org/0000-0003-2017-3227
Marion CoudercRheumatology Department, Gabriel Montpied Teachin Hospital, Clermont-Ferrand, France.
Marine BeaugerRheumatology Department, Gabriel Montpied Teachin Hospital, Clermont-Ferrand, France.
Sandrine Malochet-GuinamandRheumatology Department, Gabriel Montpied Teachin Hospital, Clermont-Ferrand, France.
Marie-Eva PickeringRheumatology Department, Gabriel Montpied Teachin Hospital, Clermont-Ferrand, France.
Martin SoubrierRheumatology Department, Gabriel Montpied Teachin Hospital, Clermont-Ferrand, France.
Anne TournadreRheumatology Department, Gabriel Montpied Teachin Hospital, Clermont-Ferrand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Capsaicin 8% patches are recommended for the treatment of localized neuropathic pain, which is a frequent reason for rheumatology consultations. Objectives: This study aimed to evaluate the efficacy and safety of capsaicin 8% used in our Rheumatology Department. Design: Single-center retrospective study. Methods: Patients treated by capsaicin 8% between October 03, 2019 and December 31, 2023 were included. Their age, sex, pain duration, DN4 score, pain intensity, and the cause of the neuropathic pain were collected. Patch safety was assessed on the day of application and after 15 days. The patient was asked about improvement, pain intensity, and the occurrence of burning sensations. Results: One hundred twelve patients (mean age 62, 70% female) were included. The causes of neuropathic pain were especially scar ( Conclusion: Capsaicin 8% appeared to be an effective treatment in localized neuropathic pain, whatever the cause. It seemed beneficial to repeat the application after the 1st one had failed. Burning sensations after placement were fairly frequent, usually moderate to high, but lasting only a short time.

Indexed as

8% capsaicin patchesefficacyneuropathic painrheumatologic diseasessafety

Identifiers

PMID40291151
PMCPMC12033592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.