ReviewMaterials today. Bio2025
Hollow microneedles as a flexible dosing control solution for transdermal drug delivery.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- In Situ Fabrication of Complex Hollow Nickel Microstructures via Filament-Guided Electrolyte-Column Electrodeposition.Micromachines · 2026Article
- Polymeric microneedles for closed-loop drug delivery: from biosensing to therapy.RSC advances · 2026Review
- Strategic selection of multi-parametric laser settings and clinical endpoints in dermatology: an engineering-to-clinical review.Lasers in medical science · 2026Review
- Comparative Evaluation of Hydrogel Dip-Coating on Cone and Pyramid Microneedle Arrays Fabricated by LCD 3D Printing.Pharmaceutics · 2026Article
- Advanced Sensing and Delivery Technologies for Nose-to-Brain Administration: From Nanocarriers to Sensor-Integrated Organ-on-Chips.Sensors (Basel, Switzerland) · 2026Review
- Enhancing Doxorubicin Bioavailability via Dissolving Microneedles: Roles of Drug Loading and Administration Force.AAPS PharmSciTech · 2026Article
- Microneedle-Assisted Delivery of Biologics: From Large Molecules to Cancer Vaccines.AAPS PharmSciTech · 2026Review
- Microneedle Technologies for Drug Delivery: Innovations, Applications, and Commercial Challenges.Micromachines · 2026Review
- Microneedle-Assisted Cell Delivery and Therapy.Research (Washington, D.C.) · 2026Review
- Deciphering the Impact of Protein Corona on Biological Fate of Nanomedicine-loaded Microneedles.Current drug metabolism · 2026Article
- Harnessing Nanocarriers to Improve Psychiatric Treatment: Progress, Limitations, and Future Directions.International journal of nanomedicine · 2026Review
- Advanced 3D bioink featuring damping and antioxidant for micro-nano fabrication.Materials today. Bio · 2025Article
- 3D nanoprinting of embryo microinjection needles with anti-clogging features.Microsystems & nanoengineering · 2025Article
- Microneedle-Tissue Interaction Across Varying Biological and Mechanical Conditions.Biosensors · 2025Article
- Article
- Advances in Microneedle Drug Delivery for Obesity: Mechanisms, Applications, and Perspectives.International journal of nanomedicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microneedles, small needle-like structures typically less than 1000 μm in length, are effective tools for transporting substances across biological barriers via minimally invasive pathways. Various microelectromechanical system (MEMS) processes enable the production of different types of microneedles, including solid, coated, dissolving, hydrogel, and hollow microneedles, each tailored to specific drug and fluid delivery mechanisms. Among these, hollow microneedles stand out for their ability to offer flexible dosage control adaptable to varying drug formulations, making them particularly promising for transdermal drug delivery systems. This review examines the fabrication processes of hollow microneedles, highlights the advantages of their hollow structure for medical applications, and discusses the key factors influencing their performance. Finally, it proposes directions for advancing these technologies in both industrial and research settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.