Evidence map›Paper›PMID 40290808›Full record

ArticleBiochemistry and biophysics reports2025

A nanoluciferase complementation-based assay for monitoring β-arrestin2 recruitment to the dopamine D

Viktor Burström, Kuiying Xu, Emilio Garro-Martínez, Robert H Mach, Kristoffer Sahlholm, Nibal Betari

Abstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Estimation of Dopamine DACS chemical neuroscience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Viktor BurströmDepartment of Medical and Translational Biology, Wallenberg Centre for Molecular Medicine, Umeå University, 901 87, Umeå, Sweden.
Kuiying XuDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104-6323, United States.
Emilio Garro-MartínezDepartment of Medical and Translational Biology, Wallenberg Centre for Molecular Medicine, Umeå University, 901 87, Umeå, Sweden.
Robert H MachDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104-6323, United States.
Kristoffer SahlholmDepartment of Medical and Translational Biology, Wallenberg Centre for Molecular Medicine, Umeå University, 901 87, Umeå, Sweden.
Nibal BetariDepartment of Medical and Translational Biology, Wallenberg Centre for Molecular Medicine, Umeå University, 901 87, Umeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Luciferase complementation assays have emerged as a simple means of monitoring receptor-effector interactions in living cells in a time-resolved manner. Here, we describe a nanoluciferase complementation assay capable of reporting on β-arrestin2 recruitment to the human dopamine D

Indexed as

G protein-coupled receptor kinaseHEK 293 cellsLuciferaseLuminescence measurements

Identifiers

PMID40290808
PMCPMC12032866

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.