ArticleVirusdisease2025
Epidemiological investigation and analysis of human papillomavirus infection and cataract development.
Article in Virusdisease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal studies indicated that human papillomavirus (HPV) transgenic mice develop cataract. Viral infections have been proposed as a potential contributing factor of cataract. This study aimed to examine the association between HPV infection and the risk of developing cataract. We enrolled 224,203 individuals diagnosed with HPV infection between January 1, 2000, and December 31, 2018, from the National Health Insurance Research Database of Taiwan. Propensity-score matching at a 1:1 ratio was conducted to obtain an HPV cohort and a matched non-HPV cohort. We used a Cox proportional hazards regression model to estimate the hazard ratio and 95% confidence interval. The adjusted hazard ratio for developing cataract was 1.36 (95% confidence interval, 1.32-1.39; Supplementary Information: The online version contains supplementary material available at 10.1007/s13337-024-00907-5.
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