Evidence map›Paper›PMID 40290752›Full record

ArticleRSC advances2025

Semi-synthesis and biological activities of heterocyclic compounds containing camphor.

Zeinab S Hamza, Wael N Hozzein, Khaled El-Adl, Mohammad K Okla, Gehad AbdElgayed, Wael A A Fadaly, Hussein S Mohamed

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zeinab S HamzaChemistry of Medicinal and Aromatic Plants Department, Research Institute of Medicinal and Aromatic Plants (RIMAB), Beni-Suef University Beni-Suef 62511 Egypt h_gendy_2010@yahoo.com Husseinshaban@rimp.bsu.edu.eg +201000800296.
Wael N HozzeinBotany and Microbiology Department, Faculty of Science, Beni-Suef University Beni-Suef Egypt.
Khaled El-AdlChemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development Cairo Egypt.
Mohammad K OklaBotany and Microbiology Department, College of Science, King Saud University P.O. Box 2455 Riyadh 11451 Saudi Arabia.
Gehad AbdElgayedIntegrated Molecular Plant Physiology Research, Department of Biology, University of Antwerp Antwerp 2020 Belgium.
Wael A A FadalyPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University Beni-Suef Egypt.
Hussein S MohamedChemistry of Medicinal and Aromatic Plants Department, Research Institute of Medicinal and Aromatic Plants (RIMAB), Beni-Suef University Beni-Suef 62511 Egypt h_gendy_2010@yahoo.com Husseinshaban@rimp.bsu.edu.eg +201000800296.ORCID https://orcid.org/0000-0001-8305-0561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer and lung cancer are two of the most prevalent and deadly malignancies worldwide. Both cancers present significant challenges in terms of effective treatment and management, highlighting the urgent need for novel therapeutic strategies that can improve patient outcomes. This study focuses on the synthesis of novel heterocyclic compounds derived from the naturally formed camphor, aimed at evaluating their cytotoxicity. The research addresses the need for effective cancer treatments by presenting compounds that demonstrate significant inhibitory effects against MCF-7 breast carcinoma cells. Among these, compound 20 exhibited remarkable potency, with an IC

Identifiers

PMID40290752
PMCPMC12023740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.