Evidence map›Paper›PMID 40290717›Full record

ReviewKardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery2025

Inflammatory myofibroblastic tumor of the lung: a comprehensive narrative review of clinical and therapeutic insights.

Vasileios Leivaditis, Marianthi Baltagianni, Elias Liolis, Nikolaos Baltayiannis, Gabriela Stanc, Efthymia Souka, Pella Batika, Konstantinos Grapatsas, Levan Tchabashvili, Konstantinos Tasios and 7 more

Abstract readReview
In one paragraph

Review in Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Inflammatory Myofibroblastic Tumor of the Lung: A Rare Find in an Elderly Female.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Vasileios LeivaditisDepartment of Cardiothoracic and Vascular Surgery, Westpfalz Klinikum, Kaiserslautern, Germany.
Marianthi BaltagianniDepartment of Nursing, School of Health Sciences and Welfare, University of Western Attica, Athens, Greece.
Elias LiolisDepartment of Oncology, General University Hospital of Patras, Patras, Greece.
Nikolaos BaltayiannisDepartment of Thoracic Surgery. 'Metaxa' Anticancer Hospital, Piraeus, Greece.
Gabriela StancDepartment of Pathology. 'Metaxa' Anticancer Hospital, Piraeus, Greece.
Efthymia SoukaDepartment of Pathology. 'Metaxa' Anticancer Hospital, Piraeus, Greece.
Pella BatikaDepartment of Cardiothoracic and Vascular Surgery, Westpfalz Klinikum, Kaiserslautern, Germany.
Konstantinos GrapatsasDepartment of Thoracic Surgery and Thoracic Endoscopy, Ruhrlandklinik, West German Lung Center, University Hospital Essen, University Duisburg-Essen Essen, Germany.
Levan TchabashviliDepartment of General Surgery, General University Hospital of Patras, Patras, Greece.
Konstantinos TasiosDepartment of General Surgery, General University Hospital of Patras, Patras, Greece.
Andreas AntzoulasDepartment of General Surgery, General University Hospital of Patras, Patras, Greece.
Dimitrios LitsasDepartment of General Surgery, General Hospital of Lamia, Lamia, Greece.
Eleftherios BeltsiosDepartment of Anesthesiology and Intensive Care, Hannover Medical School, Germany.
Manfred DahmDepartment of Cardiothoracic and Vascular Surgery, Westpfalz Klinikum, Kaiserslautern, Germany.
Athanasios PapatriantafyllouDepartment of Cardiothoracic and Vascular Surgery, Westpfalz Klinikum, Kaiserslautern, Germany.
Efstratios KoletsisDepartment of Cardiothoracic Surgery, General University Hospital of Patras, Patras, Greece.
Francesk MulitaDepartment of General Surgery, General University Hospital of Patras, Patras, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm classified by the World Health Organization as an intermediate malignancy with less than a 5% chance of metastasis. IMTs consist of myofibroblastic and spindle fibroblastic cells accompanied by inflammatory infiltration, primarily affecting patients under 16 years old, though they can also occur in adults. The etiology and pathogenesis of IMTs remain unclear, with possible contributing factors including inflammation, trauma, autoimmune diseases, prior surgery, viral infections, and uncontrolled myofibroblast proliferation. The primary treatment is complete surgical resection, which is associated with long-term survival and a significantly reduced recurrence rate of 2%, compared to 60% for incomplete resections. Chemotherapy is generally not recommended but may be necessary for unresectable tumors. Advances in histopathological diagnosis provide deeper insights into IMT biology, aiding in the selection of appropriate treatments. This paper presents a comprehensive review of the literature on this rare clinical entity.

Indexed as

inflammatory myofibroblastic tumormesenchymal tumormyofibroblastic proliferationpulmonary inflammatory myofibroblastic tumorrare lung tumor

Identifiers

PMID40290717
PMCPMC12019978

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.