Evidence map›Paper›PMID 40290711›Full record

ReviewKardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery2025

Could TachoSil application in cardiac surgery be potentially dangerous? A review of the literature.

Maciej Smreczak, Tomasz Furgoł, Konrad Gigoń, Maksymilian Ratajczak, Marcin M Jezierzański, Michał Miciak, Sebastian Krych, Remigiusz Antończyk, Tomasz Hrapkowicz

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maciej SmreczakStudent's Scientific Society, Department of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Tomasz FurgołStudent's Scientific Society, Department of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Konrad GigońStudent's Scientific Society, Department of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Maksymilian RatajczakStudent's Scientific Society, Department of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Marcin M JezierzańskiStudent's Scientific Society, Department of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Michał MiciakFaculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.
Sebastian KrychStudent's Scientific Society, Department of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Remigiusz AntończykDepartment of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Tomasz HrapkowiczDepartment of Cardiac Surgery, Transplantology, Vascular and Endovascular Surgery, School of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of TachoSil adhesive is becoming increasingly popular in surgical procedures. A special area of surgical medicine is cardiac surgery, where the adhesive makes it possible to provide hemostasis when classic anastomotic methods are insufficient. There are numerous studies available demonstrating the perioperative efficacy of TachoSil, and its ease of use in the human population. However, studies on the inflammation caused by TachoSil are widely limited to animal experiments. There is a lack of studies on human groups on TachoSil-induced inflammation in cardiac surgery. The purpose of our paper is to review the current knowledge on the use of TachoSil in animals and the incidence of inflammation, in order to determine whether there is a need for similar human studies in cardiac surgery. The paper discusses the details of this problem based on recent scientific reports.

Indexed as

adhesive sealantscardiac surgeryhemostats in cardiac surgeryTachoSil

Identifiers

PMID40290711
PMCPMC12019980

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.