Evidence map›Paper›PMID 40290698›Full record

ArticleWorld journal of clinical oncology2025

Relationship between

Hong-Chang Yang, Cheng-Feng Fu, Li-Jun Qiao, Gen-He Long, Li-Fen Yang, Biao Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hong-Chang YangDepartment of Gastroenterology, Longgang Central Hospital of Shenzhen, Shenzhen 518100, Guangdong Province, China.
Cheng-Feng FuDepartment of Oncology, Tongren People's Hospital, Tongren 554300, Guizhou Province, China. fcf930128@163.com.
Li-Jun QiaoDepartment of Basic Medical Sciences, Guizhou Health Vocational College, Tongren 554300, Guizhou Province, China.
Gen-He LongDepartment of School of Medicine, Guizhou Vocational and Technical College, Tongren 554300, Guizhou Province, China.
Li-Fen YangDepartment of Oncology, Tongren People's Hospital, Tongren 554300, Guizhou Province, China.
Biao YaoDepartment of Oncology, Tongren People's Hospital, Tongren 554300, Guizhou Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer (GC) is one of the most common malignancies worldwide, and

aimTo perform a meta-analysis to assess the relationship between HP and PD-L1 expression in patients with GC.

methodsA systematic literature review was conducted using PubMed, Embase, Cochrane Library, and Web of Science databases. Observational studies that examined the association between HP infection and PD-L1 expression in patients with GC were included. Odds ratios and 95% confidence intervals were calculated to estimate the association. Heterogeneity was assessed using Cochrane's

resultsFourteen studies involving a total of 3069 patients with GC were included. The pooled analysis showed a significant association between HP infection and increased PD-L1 expression in GC tissues (odd ratio = 1.69, 95% confidence interval: 1.24-2.29,

conclusionHP infection is associated with increased PD-L1 expression in GC, suggesting that HP status may influence the response to programmed cell death protein 1/PD-L1 blockade therapy.

Indexed as

Gastric cancerHelicobacter pyloriImmune checkpoint blockade therapyPathogenesisProgrammed cell death protein 1/programmed death-ligand 1

Identifiers

PMID40290698
PMCPMC12019281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.