ArticleWorld journal of orthopedics2025
Pathophysiology and management of crush syndrome: A narrative review.
Article in World journal of orthopedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Crush injury syndrome in earthquakes: a systematic review and meta-analysis on its frequency and complications.BMC emergency medicine · 2026Pooled it
- Pathophysiology-guided biomarkers and therapeutics for precision trauma medicine in polytrauma with musculoskeletal injuries.Military Medical Research · 2026Review
- Mortality prediction in older adults with earthquake-related trauma: a model combining MEWS and laboratory biomarkers.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Observational
- Towards comprehensive care in crush syndrome: Expanding the multidisciplinary framework.World journal of orthopedics · 2025Article
- Review
- Article
- Crush syndrome diagnosis and management in resource-constrained settings: A Delphi study.PloS one · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCrush syndrome refers to the traumatic rhabdomyolysis leading to a spectrum of disorders culminating in acute kidney injury. The burden of crush syndrome is high, and mortality can be as high as 20%. The significant bulk of knowledge is from old articles. Over the last 10 years new research has occurred on diagnosis and treatment in animal models.
aimTo overview of crush syndrome and discuss the newer advances related to the pathogenesis and management of a patient with crush syndrome.
methodsThe search of databases such as MEDLINE, Google Scholar, Web of Science, and EMBASE revealed 8226 articles. A thorough screening culminated in 83 crush syndrome articles included in this study.
resultsAcute kidney injury in crush syndrome is currently thought to be due to iron retention. The management of crush syndrome has also been updated with antioxidants, and several gases are being used to treat crush syndrome. In the end, treatment of crush syndrome also includes mental, social, and physical rehabilitation for better outcomes.
conclusionThe outcomes of crush syndrome have significantly improved with the introduction of newer treatment modalities, including antioxidants, hyperbaric oxygen therapy, and comprehensive mental, social, and physical rehabilitation.
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