Evidence map›Paper›PMID 40290575›Full record

ArticlePattern recognition2025

Brain Anatomy Prior Modeling to Forecast Clinical Progression of Cognitive Impairment with Structural MRI.

Lintao Zhang, Jinjian Wu, Lihong Wang, Li Wang, David C Steffens, Shijun Qiu, Guy G Potter, Mingxia Liu

Abstract read
In one paragraph

Article in Pattern recognition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Distribution-Guided Multi-Tracer Brain PET Synthesis from Structural MRI with Class-Conditioned Weighted Diffusion.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lintao ZhangDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Jinjian WuThe First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510031, China.
Lihong WangDepartment of Psychiatry, University of Connecticut School of Medicine, University of Connecticut, Farmington, CT 06030, USA.
Li WangDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
David C SteffensDepartment of Psychiatry, University of Connecticut School of Medicine, University of Connecticut, Farmington, CT 06030, USA.
Shijun QiuThe First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510031, China.
Guy G PotterDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.
Mingxia LiuDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Funding

Mapping the Causal Genetic-Imaging-Clinical Pathway for Alzheimer's DiseaseRF1AG082938 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Bingxin Zhao, Hongtu Zhu · 2023 to 2026
$3.6M
Optimized High-Resolution Fast Magnetic Resonance Fingerprinting with Cloud-Based ReconstructionR01NS134849 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Yong Chen, Pew-Thian Yap · 2024 to 2026
$1.9M
2/2 Phenotype Predictors of Cognitive Outcomes in Geriatric DepressionR01MH108560 · NIMH · DUKE UNIVERSITY · PI POTTER, GUY GLENN · 2016 to 2020
$1.8M
Comprehensive MR Fingerprinting for Infants and Young Children at Risk for Developmental Delays.R01HD112923 · NICHD · DUKE UNIVERSITY · PI Dan Ma, DEANNE E WILSON-COSTELLO · 2024 to 2026
$1.7M
Computational Neuroimaging MRI for Studying Early Brain Development with AutismR01MH133845 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Li Wang · 2024 to 2026
$1.5M
Multi-Site Neuroimage Harmonization for Personalized Brain Disorder AnalysisRF1AG073297 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2022 to 2022
$1.4M
Continued Development of Infant Neuroimaging Analysis ToolsR01EB037388 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Gang Li, Li Wang · 2025 to 2026
$1.2M
AI-Powered MRI Quality Control and Artifact Correction for Multi-Site StudiesR01EB035160 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Pew-Thian Yap · 2024 to 2026
$1.2M
Multi-Site Neuroimage Harmonization for Personalized Brain Disorder AnalysisR01AG073297 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mingxia Liu · 2025 to 2026
$922k
NIA NIH HHS R01 AG073297NIA NIH HHS RF1 AG073297NIA NIH HHS RF1 AG082938NIBIB NIH HHS R01 EB035160NIBIB NIH HHS R01 EB037388NICHD NIH HHS R01 HD112923NIMH NIH HHS R01 MH108560NIMH NIH HHS R01 MH133845NINDS NIH HHS R01 NS134849
6 · The paper itself

Abstract

Brain structural MRI has been widely used to assess the future progression of cognitive impairment (CI). Previous learning-based studies usually suffer from the issue of small-sized labeled training data, while a huge amount of structural MRIs exist in large-scale public databases. Intuitively, brain anatomical structures derived from these public MRIs (even without task-specific label information) can boost CI progression trajectory prediction. However, previous studies seldom use such brain anatomy structure information as priors. To this end, this paper proposes a brain anatomy prior modeling (BAPM) framework to forecast the clinical progression of cognitive impairment with small-sized target MRIs by exploring anatomical brain structures. Specifically, the BAPM consists of a

Indexed as

Brain anatomyCognitive impairmentMRIPrediction

Identifiers

PMID40290575
PMCPMC12021437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.