Evidence map›Paper›PMID 40290474›Full record

ArticleFrontiers in veterinary science2025

High pathogenicity of emerging porcine G9P[23] and G11P[7] rotavirus for newborn piglets in China.

Zhendong Zhang, Duo Li, Sun He, Jiubin Du, Yubo Li, Qiangde Liu, Pengjiang Wang, Wenqiang Wang, Wei Wen, Zhenbang Zhu and 2 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhendong ZhangJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Duo LiJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Sun HeTECON Biopharmaceutical Co., Ltd., Ürümqi, China.
Jiubin DuTECON Biopharmaceutical Co., Ltd., Ürümqi, China.
Yubo LiJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Qiangde LiuTECON Biopharmaceutical Co., Ltd., Ürümqi, China.
Pengjiang WangTECON Biopharmaceutical Co., Ltd., Ürümqi, China.
Wenqiang WangJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Wei WenJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhenbang ZhuJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Xudong TangSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.
Xiangdong LiJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to better understand the pathogenicity of the current porcine A group rotavirus (PoRVA) field strains, AHBZ2304 (G9P[23]) and AHBZ2303 (G11P[7]) isolated from diarrhea suckling piglets were selected for pathogenicity analysis in the present study. Experimental inoculation of colostrum-deprived 2-day-old piglets revealed that both isolates caused severe clinical sings, high level of virus shedding and significant damage to the small intestinal villi. Additionally, both gross and microscopic lung lesions were identified at 72 h post infection (HPI) compared to control. Alterations in the microbiota and the overexpression of inflammatory cytokines may serve as critical mechanisms driving the bowel disease associated with PoRVA infection. Our results are of great significance for understanding the pathogenicity of PoRVA emerged in recent years, highlighting the potential for porcine rotavirus to become epidemic and complex, and necessitating heightened attention of the often-overlooked disease in the field.

Indexed as

G11P[7]G9P[23]pathogenicitypigletsporcine group A rotavirus

Identifiers

PMID40290474
PMCPMC12031660

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.