Evidence map›Paper›PMID 40290415›Full record

ArticleAmerican journal of preventive cardiology2025

Disparities in statin use following identification of coronary artery calcium.

Charlotte C Ellberg, Kavenpreet Bal, Edward Duran, Michael H Criqui, Michael D Shapiro, Harpreet S Bhatia

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charlotte C EllbergDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Kavenpreet BalKaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA, USA.
Edward DuranDivision of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Michael H CriquiDivision of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Michael D ShapiroCenter for the Prevention of Cardiovascular Disease, Section on Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Harpreet S BhatiaDivision of Cardiovascular Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, USA.

Funding

UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
Aspirin for Primary Prevention of Cardiovascular Disease in Patients with Elevated Lipoprotein(a)K08HL166962 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Harpreet Singh Bhatia · 2023 to 2026
$676k
NHLBI NIH HHS K08 HL166962NHLBI NIH HHS R25 HL145817
6 · The paper itself

Abstract

Background: Coronary artery calcium (CAC) scoring is a useful tool for risk stratification in asymptomatic individuals, and current clinical practice is to utilize statins in individuals with CAC. A growing body of research has aimed to identify and mitigate health disparities and their relation to cardiovascular disease (CVD) risk. Likewise, studies have highlighted social determinants of health (SDOH) that contribute to health disparities in CVD. Objectives: We aimed to evaluate whether disparities exist with regards to statin use after identification of CAC within the Multi-Ethnic Study of Atherosclerosis (MESA). Methods: The associations between race/ethnicity, age, sex, primary language, and an aggregate SDOH score (calculated using previously defined methods) with statin use at short- and long-term follow-up were evaluated in logistic regression models with adjustment for traditional CVD risk factors in individuals with baseline CAC>0 without baseline statin use. Results: In the overall cohort, 3416 participants had CAC = 0, 1794 CAC 1-99, 757 CAC 100-300, and 847 CAC>300 AU Mean age was 62 (10.2) years, 53 % ( Conclusions: This study identifies disparities in statin use by race/ethnicity, language, and social determinants of health after identification of CAC. While CAC is an effective tool for identifying atherosclerosis in asymptomatic individuals, more equitable use of subsequent therapy is needed.

Indexed as

Coronary artery calciumDisparitiesStatin

Identifiers

PMID40290415
PMCPMC12022484

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.