ArticleInfection and drug resistance2025
Cryosurgery and Next-Generation Sequencing Unravel Talaromycosis Mimicking an Airway Tumor: A Case Report.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Tracheobronchial talaromycosis is uncommon in non-HIV infected patients. Reports on tracheobronchial talaromycosis presenting as a tumor-like lesion are also scarce, and the value of bronchoscopic cryosurgery in the treatment of tracheobronchial talaromycosis has not been mentioned. We report a case of tracheobronchial talaromycosis mimicking an airway tumor, which was diagnosed through bronchoscopic cryosurgery, next-generation sequencing(NGS), and tissue culture. The patient presented with neoplastic lesions in the airway and tested positive for anti-interferon-gamma autoantibody(AIGA). Clinical cure was achieved through bronchoscopic cryosurgery followed by a 2-week course of intravenous amphotericin B infusion and atomization induction therapy, along with 3 months of oral voriconazole maintenance therapy. In addition, we collected six reports summarizing the clinical data of tracheobronchial
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