ArticlePakistan journal of medical sciences2025
Clinical efficacy of transjugular intrahepatic portosystemic shunt in treating esophageal variceal bleeding in patients with liver cirrhosis.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To explore the clinical efficacy of transjugular intrahepatic portal vein shunt (TIPS) in treating esophageal variceal bleeding (EVB) of liver cirrhosis patients. Methods: Clinical data of 60 patients with liver cirrhosis and EVB, admitted to The Second Affiliated Hospital of Bengbu Medical College between from November 2017 to April 2024, were retrospectively analyzed. Of them, 31 received TIPS treatment (TIPS group), and 29 received treatment with somatostatin (SST group). Blood transfusion volume, hemostasis time, and the length of hospital stay were compared between the two groups. Hemodynamic status, gastric motility indicators, vascular endothelial function indicators, levels of total bilirubin (TBIL), albumin (ALB), and international normalized ratio (INR) of both groups were compared before and after the treatment. The rebleeding and prognosis of patients were assessed after 6 months of follow-up. Results: The blood transfusion volume, hemostasis time, and length of hospital stay were significantly lower in the TIPS group than in the SST group ( Conclusions: Compared with conventional drug therapy, TIPS treatment can more effectively regulate hemodynamic status, improve gastric motility and vascular endothelial function, and reduce re-bleeding and mortality of patients with liver cirrhosis complicated by EVB.
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