Evidence map›Paper›PMID 40290116›Full record

ArticleInverse problems2020

Method of moments for 3D single particle

Nir Sharon, Joe Kileel, Yuehaw Khoo, Boris Landa, Amit Singer

Abstract read
In one paragraph

Article in Inverse problems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Subspace Method of Moments forSIAM journal on imaging sciences · 2026
    Article
  4. FAST EXPANSION INTO HARMONICS ON THE BALL.SIAM journal on scientific computing : a publication of the Society for Industrial and Applied Mathematics · 2025
    Article
  5. TheApplied and computational harmonic analysis · 2024
    Article
  6. Article
  7. Article
  8. Autocorrelation analysis for cryo-EM with sparsity constraints: Improved sample complexity and projection-based algorithms.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. MULTI-TARGET DETECTION WITH ROTATIONS.Inverse problems and imaging (Springfield, Mo.) · 2023
    Article
  10. Article
  11. Article
  12. Super-resolution multi-reference alignment.Information and inference : a journal of the IMA · 2022
    Article
  13. Article
  14. Wavelet invariants for statistically robust multi-reference alignment.Information and inference : a journal of the IMA · 2021
    Article
  15. Wilson statistics: derivation, generalization and applications to electron cryomicroscopy.Acta crystallographica. Section A, Foundations and advances · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nir SharonSchool of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0001-6329-3857
Joe KileelProgram in Applied and Computational Mathematics, Princeton University, Princeton, NJ, United States of America.
Yuehaw KhooDepartment of Statistics and the College, The University of Chicago, Chicago, IL, United States of America.
Boris LandaApplied Mathematics Program, Yale University, New Haven, CT, United States of America.
Amit SingerProgram in Applied and Computational Mathematics and Department of Mathematics, Princeton University, Princeton, NJ, United States of America.

Funding

Improved Algorithms for Macromolecular Structure Determination by cyro-EMR01GM090200 · NIGMS · PRINCETON UNIVERSITY · PI SINGER, AMIT · 2009 to 2017
$2.8M
NIGMS NIH HHS R01 GM090200
6 · The paper itself

Abstract

Single-particle reconstruction in cryo-electron microscopy (cryo-EM) is an increasingly popular technique for determining the 3D structure of a molecule from several noisy 2D projections images taken at unknown viewing angles. Most reconstruction algorithms require a low-resolution initialization for the 3D structure, which is the goal of

Indexed as

ab initio modelingautocorrelation analysiscryo-EMmethod of momentsnon-convex optimizationspherical harmonicsWigner matrices

Identifiers

PMID40290116
PMCPMC12030009

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.