Evidence map›Paper›PMID 40290019›Full record

Trial reportNutrients2025

Bifidogenic Effect of 2'-Fucosyllactose (2'-FL) on the Gut Microbiome of Healthy Formula-Fed Infants: A Randomized Clinical Trial.

Tamara Lazarini, Karina Merini Tonon, Humberto Bezerra de Araujo Filho, Mauro Batista de Morais

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tamara LazariniNutrition Postgraduate Program, Universidade Federal de São Paulo, São Paulo 04023-062, Brazil.ORCID 0000-0003-0085-6944
Karina Merini TononDepartment of Environmental & Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.ORCID 0000-0002-5938-7831
Humberto Bezerra de Araujo FilhoDivision of Pediatric Gastroenterology, Universidade Federal de São Paulo, São Paulo 04023-062, Brazil.ORCID 0000-0001-6438-0995
Mauro Batista de MoraisNutrition Postgraduate Program, Universidade Federal de São Paulo, São Paulo 04023-062, Brazil.ORCID 0000-0003-4014-5549

Funding

Nestlé (Brazil) 0000
6 · The paper itself

Abstract

Breast milk is rich in bioactive components, especially human milk oligosaccharides (HMOs), which are crucial for establishing gut microbiota. The 2'-FL (2-Fucosyllactose), one of the most abundant oligosaccharides in breast milk, functions as a selective prebiotic.

Indexed as

Gastrointestinal MicrobiomeInfant FormulaPrebioticsTrisaccharidesBifidobacteriumBreast FeedingFecesFemaleHumansInfantMaleMilk, HumanOligosaccharidesRNA, Ribosomal, 16S2'-fucosyllactoseOligosaccharidesPrebioticsRNA, Ribosomal, 16STrisaccharides2-fucosyllactosebreast milkfructo-oligosaccharidesgalacto-oligosaccharidesgut microbiomehuman milk oligosaccharidesinfant formula

Identifiers

PMID40290019
PMCPMC11944528

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.