Evidence map›Paper›PMID 40289975›Full record

ReviewCurrent pharmaceutical design2025

Nano Selenium: A Promising Solution for Infectious Diseases - Current Status and Future Prospects.

Shaheen Husain, Rania Mohammad Sabri Sultan, Kirti Saxena, Fareha Bano, Rajat Goyal, Shivani Chopra, Hitesh Chopra, Suresh K Verma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shaheen HusainAmity Institute of Pharmacy, Amity University Uttar Pradesh (AUUP), Sec. 125, Noida, 201313, India.
Rania Mohammad Sabri SultanDepartment of Microbiology, Faculty of Science, King Abdul Aziz University, Jeddah, 21589, Saudi Arabia.
Kirti SaxenaAmity Institute of Nanotechnology, Amity University Uttar Pradesh (AUUP), Sec. 125, Noida, 201313, India.
Fareha BanoDepartment of Biology, Faculty of Science and Arts, Taibah University (Female Branch) Al Ula Campus, Al Madinah Al Munawarah, Kingdom of Saudi Arabia.
Rajat GoyalMM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, 133207, India.
Shivani ChopraDepartment of Biosciences, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
Hitesh ChopraCentre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, 140401, Punjab, India.
Suresh K VermaKIIT School of Biotechnology, KIIT University, Bhubaneswar, 751024, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to increasing antibiotic resistance, researchers are investigating the medicinal potential of nanoparticles, particularly their antibacterial and antiviral properties. Among other things, this concern mandates the journey for novel and more potent antibacterial drugs. The crucial role of nanoparticles in the treatment of various microbial diseases has been demonstrated in several research studies. AIM &

objectiveThis study focuses on the role of Selenium nanoparticles (SeNPs) against infectious diseases, with an emphasis on exploring their probable mechanisms of action. METHODOLOGY: Nanoparticles have been exploited as delivery mechanisms and broad-spectrum inhibitors in viral and microbial studies. Their significant therapeutic potential stems from their high surface area to volume ratio, which enables diverse applications. Various materials have been employed in the synthesis of nanoparticles, each tailored to meet specific therapeutic requirements. The unique combination of biological relevance, environmental friendliness, and versatile applications makes SeNPs a promising alternative to other nanoparticles in various fields.

resultsThe therapeutic potential of nanoparticles, especially Selenium nanoparticles (SeNPs), is significant and warrants further exploration. They have shown promise as delivery agents and potent materials for combating infectious diseases, making them a valuable asset in the fight against antibiotic resistance.

conclusionSelenium nanoparticles (SeNPs) are potential biological prospects because of their biocompatibility, bioavailability, and low toxicity. Size, shape, and synthesis affect SeNP uses in biological systems. SeNPs are chemopreventive, anti-inflammatory, and antioxidant medicines that may cure fungal, bacterial, and parasite infections, cancer, and diabetes. They have better absorption, bioavailability, and antibacterial action than micron-size particles. Their large surface area facilitates biological contact and bioactive chemical functionalization. Functionalized SeNPs are less cytotoxic than other seleniums. They prevent DNA oxidation, detoxify heavy metals, and inhibit hydroxyl radicals. In conclusion, selenium nanoparticles have considerable promise for medication delivery, antimicrobials, and cancer and diabetes treatment. They are attractive nanomedicine prospects due to their low toxicity, biocompatibility, and high bioavailability.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsCommunicable DiseasesNanoparticlesSeleniumAnimalsHumansAnti-Bacterial AgentsAnti-Infective AgentsSeleniumbacteriafungus.infectious diseasenanotechnologySeNPsvirus

Identifiers

PMID40289975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.