Evidence map›Paper›PMID 40289696›Full record

ArticleBritish journal of haematology2025

PF4-associated immune thrombocytopenia and thrombosis (PITT)-More than heparin and vaccines.

Michael Makris

Abstract readCase Reports
In one paragraph

Article in British journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael MakrisSchool of Medicine and Population Health, University of Sheffield, Sheffield, UK.ORCID https://orcid.org/0000-0001-7622-7939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A young woman presented with portal vein thrombosis and thrombocytopenia and developed further extensive thrombosis following treatment with heparin. Despite no previous heparin exposure, she was found to be strongly positive for anti-platelet factor 4 (PF4) antibodies. She had acute cytomegalovirus (CMV) infection and a monoclonal gammopathy. Commentary on: Nicolson et al. Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics. Br J Haematol 2025; 206:1737-1742.

Indexed as

AutoantibodiesCytomegalovirus InfectionsHeparinPlatelet Factor 4Purpura, Thrombocytopenic, IdiopathicThrombosisAdultFemaleHumansThrombocytopeniaAutoantibodiesHeparinPF4 protein, humanPlatelet Factor 4anti‐PF4HITPITTVITT

Identifiers

PMID40289696
PMCPMC12166333

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.