ArticleWork (Reading, Mass.)2025
Physical activity and sedentariness levels in patients with post-exertional malaise resulting from post-COVID-19 syndrome.
Article in Work (Reading, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Pathophysiological mechanisms of post-exertional malaise: an integrative analysis based on the metabolism-immune-neuro interaction model.Frontiers in immunology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundPost-exertional malaise (PEM) is a complex phenomenon characterized by extreme fatigue, reduced endurance, and muscular and joint pains. Physical activity (PA) has recognized health benefits, including reducing the risks of chronic diseases and mortality. During the pandemic, a general decline in PA was measured, but the profile of the various components of PA and sedentariness in patients with PEM resulting from post-COVID-19 syndrome (PCS-19) remains scarce. It is relevant to observe the impact of these discomforts on PQ after their occurrence.ObjectiveThis study examines the detailed PA and sedentary profile of individuals affected by PEM associated with PCS-19.MethodsAn online questionnaire disseminated via social media platform evaluated PA and sedentariness before and after COVID-19 diagnostic.ResultsIndividuals with PEM (n = 154) became more sedentary and inactive post-COVID-19. Specifically, PA at work decreased in women and those whose last infection occurred over a year ago. Walk decreased for women but increased for men. Bike journeys generally decreased after COVID-19. The severity of PEM, the pace of recovery, and fear of malaise influenced PA changes.ConclusionsThe PCS-19 leads to increased sedentary behavior and a decline in PA, particularly at work, and is more pronounced among women and those more severely affected by PEM. These findings are critical for post-COVID PA resumption, including for workers who go back to work and who regain normal duties while being potentially deconditioned.
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