Evidence map›Paper›PMID 40289536›Full record

ReviewHuman vaccines & immunotherapeutics2025

The microbiological characteristics and diagnosis of

Chih-Ho Chen, Chyi-Liang Chen, Lin-Hui Su, Chih-Jung Chen, Ming-Han Tsai, Cheng-Hsun Chiu

Abstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chih-Ho ChenDepartment of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Chyi-Liang ChenMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Lin-Hui SuMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chih-Jung ChenMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Ming-Han TsaiMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Cheng-Hsun ChiuMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID 0000-0003-4324-7743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two pneumococcal conjugate vaccines, PCV15 and PCV20, were licensed in June 2021. PCV15 includes two additional serotypes (22F, 33F) beyond those in PCV13, while PCV20 adds seven more (8, 10A, 11A, 12F, 15B, 22F, 33F), covering approximately 30% of invasive pneumococcal disease (IPD) cases in adults. In June 2023, the US CDC's Advisory Committee on Immunization Practices (ACIP) recommended either PCV15 or PCV20 for all children aged < 5 years and children aged 2‒18 years with risk conditions. In June 2024, the FDA approved PCV21 for adults ≥ 18 years. In October 2024, ACIP recommended either PCV20 or PCV21 alone or PCV15 with PPSV23 for adults ≥ 50 years or 19-49 years with risk conditions. These advancements highlight the evolving landscape of pneumococcal vaccination. This review examines the molecular epidemiology of pneumococcal infections, advancements in diagnostic methods, and the anticipated public health impact of these vaccines in reducing pneumococcal disease burden.

Indexed as

Pneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeAdolescentAdultChildChild, PreschoolHumansMiddle AgedSerogroupUnited StatesVaccines, ConjugateYoung AdultPneumococcal VaccinesVaccines, Conjugateadvisory committee on immunization practicesconjugate vaccineinvasive pneumococcal diseaseserotypeStreptococcus pneumoniae infection

Identifiers

PMID40289536
PMCPMC12039398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.