Evidence map›Paper›PMID 40289473›Full record

ReviewThe New phytologist2025

Regeneration and defense: unveiling the molecular interplay in plants.

Dawei Xu, Li Yang

Abstract readReview
In one paragraph

Review in The New phytologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cytokinin-supplemented medium drivesFrontiers in plant science · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dawei XuDepartment of Plant Pathology, College of Agricultural & Environmental Sciences, University of Georgia, Athens, GA, 30602, USA.ORCID https://orcid.org/0000-0002-8906-7070
Li YangDepartment of Plant Pathology, College of Agricultural & Environmental Sciences, University of Georgia, Athens, GA, 30602, USA.ORCID https://orcid.org/0000-0003-3665-544X

Funding

Dissect the Timing Mechanism for Immune Maturation in PlantsR35GM143067 · NIGMS · UNIVERSITY OF GEORGIA · PI Li Yang · 2021 to 2026
$1.7M
National Science Foundation IOS-2039313NIGMS NIH HHS R35 GM143067NIGMS NIH HHS R35GM143067
6 · The paper itself

Abstract

In both plants and animals, tissue or organ regeneration typically follows wounding, which also activates defense responses against pathogenic microbes and herbivores. Both intrinsic and environmental cues guide the molecular decisions between regeneration and defense. In animal studies, extensive research has highlighted the role of various microbes - including pathogenic, commensal, and beneficial species - in influencing the signaling interplay between immunity and regeneration. Conversely, most plant regeneration studies are conducted under sterile conditions, which leaves a gap in our understanding of how plant innate immunity influences regeneration pathways. Recent findings have begun to elucidate the roles of key defense pathways in modulating plant regeneration and the crosstalk between these two processes. These studies also explore how microbes might influence the molecular choice between defense and regeneration in plants. This review examines the molecular mechanisms governing the balance between plant regeneration and innate immunity, with a focus on the emerging role of aging and microbial interactions in shaping these processes.

Indexed as

Plant ImmunityPlantsRegenerationImmunity, InnateSignal Transductiondefense‐growth crosstalkdisease resistanceimmunity–regeneration balanceplant innate immunityregeneration

Identifiers

PMID40289473
PMCPMC12095984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.