Evidence map›Paper›PMID 40289384›Full record

ReviewImmunity, inflammation and disease2025

Research Progress of Plasma Cell Mastitis.

Zhebin Liang, Lifeng Zhang

Abstract readReview
In one paragraph

Review in Immunity, inflammation and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhebin LiangDepartment of General Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.ORCID 0009-0004-9447-2398
Lifeng ZhangDepartment of General Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.ORCID 0009-0007-9086-5890

Funding

This research was supported by the Science and Technology Program of Suzhou, Grant SZM2022002.
6 · The paper itself

Abstract

backgroundPlasma cell mastitis (PCM), also termed mammary duct ectasia, is a chronic nonbacterial inflammatory disease characterized by mammary duct dilation and plasma cell infiltration. Due to its varied and nonspecific clinical presentation, PCM is frequently misdiagnosed as breast cancer, complicating clinical management.

objectivesThis review aims to summarize recent advances in the understanding of PCM, focusing on its etiology, clinical manifestations, diagnosis, and treatment strategies, as well as clarifying differential diagnostic points with granulomatous mastitis (GLM).

methodsWe reviewed recent literature highlighting clinical characteristics, diagnostic approaches, and therapeutic options related to PCM, including comparative studies addressing differences between PCM and GLM. DISCUSSION: Recent progress has enhanced understanding of PCM's clinical and pathological features, yet distinguishing PCM from GLM remains clinically challenging due to overlapping presentations. An integrated approach involving clinical evaluation, imaging modalities, and histopathological examination is recommended to improve diagnostic accuracy and clinical outcomes.

conclusionFurther investigation into the pathogenesis of PCM is essential for developing more precise diagnostic criteria and effective treatments, ultimately improving patient prognosis and reducing misdiagnosis.

Indexed as

MastitisPlasma CellsBreast NeoplasmsDiagnosis, DifferentialFemaleGranulomatous MastitisHumansgranulomatous mastitisIL‐6/JAK2/STAT3 pathwaymammary duct ectasiaplasma cell mastitis

Identifiers

PMID40289384
PMCPMC12034746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.