Evidence map›Paper›PMID 40289267›Full record

ReviewBritish journal of clinical pharmacology2025

Appraising the visibility, relevance and impacts of clinical pharmacology.

Serge Cremers, Samuel L M Arnold, Nilima A Kshirsagar, Catriona Waitt, Olayinka O Ogunleye, Lars L Gustafsson

Abstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Serge CremersDepartment of Pathology & Cell Biology and Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Centre, New York, New York, USA.ORCID https://orcid.org/0000-0002-6800-5532
Samuel L M ArnoldDepartment of Pharmaceutics, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-8290-2347
Nilima A KshirsagarFormer National Chair Clinical Pharmacology, Division of Basic Medical Sciences, Indian Council of Medical Research, New Delhi, India.ORCID https://orcid.org/0000-0002-9195-3143
Catriona WaittResearch Department, Infectious Diseases Institute, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0003-0134-5855
Olayinka O OgunleyeDepartments of Pharmacology & Medicine, Lagos State University College of Medicine, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-8921-1909
Lars L GustafssonDivision of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0063-552X

Funding

European Union RIA2016MC-1606
6 · The paper itself

Abstract

aimsClinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.

methodsLiterature consultations and multiple survey approaches through personal contacts with leading experts from high-income countries, Asia and Africa and with CP scientific journal editors with presentation, discussion and recommendations at a workshop (World Congress in Basic and Clinical Pharmacology, Glasgow 2023).

resultsHistorically, CP has been a leading discipline for the advancement of knowledge and practice of rational principles for human drug use. However, currently there is variable visibility and impact between countries in research, education and clinical services. The workshop participants agreed that CP continues to be an open transdisciplinary subject to address challenges of drug development with affordable access to essential medicines and rational use of new advanced therapies as well as essential medicines. Medical specialisation programmes in clinical pharmacology and therapeutics should be the norm and become attractive through introducing board programmes for accreditation of specialists building on models existing in some European countries, India, Nigeria and South Africa.

conclusionsClinical pharmacologists should collaborate across countries and disseminate success stories, demonstrating their essential contributions to medical science and patient care. A white book with comprehensive global representation on the future role, structure and impact of the discipline should be developed.

Indexed as

Pharmacology, ClinicalDrug DevelopmentHumansclinical pharmacologyglobal impactpolicy makingrational use of medicinesspecializationtherapeutics

Identifiers

PMID40289267
PMCPMC12199104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.