Evidence map›Paper›PMID 40289239›Full record

ReviewProbiotics and antimicrobial proteins2025

Food, Health, and Environmental Impact of Lactic Acid Bacteria: The Superbacteria for Posterity.

Patrick Othuke Akpoghelie, Great Iruoghene Edo, Alice Njolke Mafe, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Ali B M Ali, Emad Yousif, Joseph Oghenewogaga Owheruo, Splendour Oberhiri Oberhiri, Arthur Efeoghene Athan Essaghah and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Antibacterial Activities of Predicted AMP inInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Patrick Othuke AkpoghelieDepartment of Food Science and Technology, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria.
Great Iruoghene EdoDepartment of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria. greatiruo@gmail.com.
Alice Njolke MafeDepartment of Biological Sciences, Faculty of Science, Taraba State University Jalingo, Taraba State, Jalingo, Nigeria.
Endurance Fegor IsojeFaculty of Science, Department of Science Laboratory Technology (Biochemistry Option), Delta State University of Science and Technology, Ozoro, Nigeria.
Ufuoma Augustina IgbukuDepartment of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria.
Ali B M AliDepartment of Air Conditioning Engineering, College of Engineering, Warith Al-Anbiyaa University, Karbala, Iraq.
Emad YousifDepartment of Chemistry, College of Sciences, Al-Nahrain University, Baghdad, Iraq.
Joseph Oghenewogaga OwheruoDepartment of Food Science and Technology, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria.
Splendour Oberhiri OberhiriDepartment of Natural Science, University of Lincoln, Lincolnshire, UK.
Arthur Efeoghene Athan EssaghahFaculty of Environmental Sciences, Department of Urban and Regional Planning, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria.
Dina S AhmedDepartment of Chemical Industries, Institute of Technology-Baghdad, Middle Technical University, Baghdad, Iraq.
Huzaifa UmarOperational Research Centre in Healthcare, Near East University, Nicosia, Cyprus.
Ahmed A AlamieryAUIQ, Al-Ayen Scientific Research Center, Al-Ayen Iraqi University, P.O. Box: 64004, An Nasiriyah, Thi Qar, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic acid bacteria (LAB) are Gram-positive cocci or rods that do not produce spores or respire. Their primary function is to ferment carbohydrates and produce lactic acid. The two primary forms of LAB that are currently recognized are homofermentative and heterofermentative. This review discusses the evolutionary diversity and the biochemical and biophysical conditions required by LAB for their metabolism. Next, it concentrates on the applications of these bacteria in gut health, cancer prevention, and overall well-being and food systems. There are numerous uses for LAB, including the food and dairy sectors, as probiotics to improve human and animal gut-health, as anti-carcinogenic agents, and in food safety as biopreservatives, pathogen inhibitors, and reducers of anti-nutrients in foods. The group included many genera, including Aerococcus, Carnobacterium, Enterococcus, Lactobacillus, Lactococcus, Leuconostoc, Streptococcus, Tetragenococcus, Vagococcus, and Weissella. Numerous species of Lactobacillus and Bifidobacterium genera as well as other microbes have been suggested as probiotic strains, or live microorganisms added to meals to improve health. LAB can colonize the intestine and take part in the host's physiological processes. This review briefly highlights the role of these bacteria in food safety and security as well as aspects of regulation and consumer acceptance. Finally, the recent innovations in LAB fermentations and the limitations and challenges of the applications of LAB in the food industry are discussed. Notwithstanding recent developments, the study of LAB and their functional components is still an emerging topic of study that has not yet realized its full potential.

Indexed as

Food MicrobiologyLactobacillalesProbioticsAnimalsFermentationHumansFood safetyHealthLactic acid bacteriaProbiotics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.