ArticleWorld journal of microbiology & biotechnology2025
The influence of 2,6-Di-tert-butyl-p-cresol stress on the microalga Phaeodactylum tricornutum and phycosphere bacteria community.
Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Microalgae-Bacteria Interactions in the Bio-based Circular Economy: Mechanisms and Biotechnological Applications.Current microbiology · 2026Review
- Effect Produced by a Mixture of Phenol,Toxics · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
The emerging contaminant 2, 6-di-tert-butyl-p-cresol (BHT) is a kind of synthetic phenolic antioxidant and can pose negative effects on the aquatic organism. However, the mechanism of phycosphere bacteria coordinating with microalgae in response to BHT stress remains poorly understood. Herein, the effect of BHT on the microalgae Phaeodactylum tricornutum was comprehensively analyzed. BHT exposure led to a dose-dependent inhibition of P. tricornutum growth and the photosynthetic pigment biosynthesis. BHT also led to an increase in the content of malondialdehyde, therefore microalgae responded to the oxidative stress by enhancing activities of antioxidant enzymes, including superoxide dismutase, catalase and peroxidase, to eliminate excess reactive oxygen species in the cells. Furthermore, transcriptome analysis revealed that genes related to photosynthesis, TCA cycle, oxidative phosphorylation, and indole-3-acetic acid (IAA) synthesis were up-regulated in response to BHT stress, which are crucial for the microalgae's adaptation to stresses. In addition, high-throughput Illumina MiSeq sequencing results demonstrated a significant increase in the relative abundance of bacteria affiliated with Halomonas, Marivita and Oceanicaulis. Microbiological assays demonstrated that Halomonas can thrive by using BHT as the sole energy source and exhibit a chemotactic response to IAA. Therefore, we conclude that the increased content of IAA secreted by microalgae in the phycosphere environment promoted the enrichment of BHT-tolerant bacterium Halomonas, thereby it is helpful for environmental pressures adaptability of P. tricornutum. Overall, this study provided a comprehensive understanding of the physiological and biochemical effects of BHT on microalgae, and we highlight the potential functional significance of IAA in establishing an interaction between microalgae and algae-associated bacteria in adverse environments.
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Registered trials
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