Evidence map›Paper›PMID 40289157›Full record

ArticleTropical diseases, travel medicine and vaccines2025

Evidence of pathogens associated with travelers' diarrhea in Thailand: a systematic review.

Wanida Mala, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Kinley Wangdi, Polrat Wilairatana, Manas Kotepui

Abstract read
In one paragraph

Article in Tropical diseases, travel medicine and vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wanida MalaMedical Technology, Faculty of Science, Nakhon Phanom University, Nakhon Phanom, Thailand.
Kwuntida Uthaisar KotepuiMedical Technology, Faculty of Science, Nakhon Phanom University, Nakhon Phanom, Thailand.
Frederick Ramirez MasangkayDepartment of Medical Technology, Faculty of Pharmacy, University of Santo Tomas, Manila, 1008, Philippines.
Kinley WangdiHEAL Global Research Centre, Health Research Institute, Faculty of Health, University of Canberra, Bruce, ACT, 2617, Australia.
Polrat WilairatanaDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
Manas KotepuiMedical Technology, Faculty of Science, Nakhon Phanom University, Nakhon Phanom, Thailand. manaskote@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThailand, a major tourist destination, exhibits variations in sanitation and food safety practices that can lead to cases of travelers' diarrhea (TD) caused by a plethora of pathogens. This systematic review synthesizes data on the pathogens associated with TD in Thailand, providing valuable insights into pathogen diversity and distribution, traveler profiles, and geographical regions of concern.

methodsThis systematic review followed the PRISMA guidelines and was registered in PROSPERO (CRD42022346014). A comprehensive search was conducted across PubMed, Embase, Scopus, MEDLINE, and Journals@Ovid databases. The search included terms related to "diarrhea," "travelers," and "Thailand," without restrictions on publication date. Eligible studies focused on travelers to Thailand who developed diarrhea with identified specific pathogens. Data was extracted and synthesized using a narrative approach. The risk of bias was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist.

resultsA total of 15 studies met the eligibility criteria, identifying that pathogens related to TD in Thailand were bacteria, particularly enterotoxigenic Escherichia coli (ETEC) (80%), followed by Campylobacter jejuni (33.3%) and Salmonella spp. (40%). Viral pathogens such as rotavirus and norovirus were also notable, with Giardia spp. being the most identified parasite. Pathogen distribution varied across different regions of Thailand, with tourism hubs such as Bangkok, Chiang Mai, Phuket, and Krabi reporting a broader range of infections.

conclusionsThis systematic review highlights the diverse range of pathogens associated with TD in Thailand, with bacterial pathogens, specifically ETEC, being the predominant cause in most studies. The findings underscore the importance of preventive measures, such as improved hygiene practices and food safety awareness, especially in high-risk tourist areas. Further research is needed to understand better the risk factors contributing to TD and to develop targeted interventions for prevention.

Indexed as

Enterotoxigenic Escherichia coliETECSystematic reviewThailandTravelers’ diarrhea

Identifiers

PMID40289157
PMCPMC12036122

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.