ArticleItalian journal of pediatrics2025
Clinical features and risk factors of adenovirus-related plastic bronchitis in children.
Article in Italian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Clinical characteristics and inflammatory response of adenovirus viremia in children with severe adenoviral pneumonia: a prospective cohort study.BMC infectious diseases · 2026Article
- A Predictive Nomogram for Severe RSV Infection in Children: A Retrospective, Single-Center Development and Validation Study.Journal of inflammation research · 2026Article
- Early prediction of plastic bronchitis in pediatric patients withFrontiers in cellular and infection microbiology · 2026Article
- Risk Factor Analysis of Mycoplasma pneumoniae Pneumonia Complicated With Plastic Bronchitis in Children: A Single-Center Retrospective Study.The clinical respiratory journal · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundTo analyze the clinical characteristics of children with adenoviral pneumonia, identify independent risk factors for early prediction of plastic bronchiolitis (PB), and develop a predictive nomogram.
methodsThis retrospective study analyzed the clinical data of children diagnosed with adenoviral pneumonia. Patients were categorized into PB and non-PB groups. General characteristics, clinical symptoms, laboratory findings, and imaging results were compared between the two groups. Multivariate logistic regression was used to identify significant risk factors, and a nomogram model was constructed.
resultsAmong the 164 patients, 139 were in the non-PB group and 25 were in the PB group. Multivariate logistic regression identified diminished breath sounds, D-dimer (D-D) levels, and Lactic dehydrogenase (LDH) levels as significant risk factors for PB. The nomogram developed from these factors had an area under the receiver operating characteristic curve (AUC) of 0.904 (95% confidence interval: 0.847-0.960). The Hosmer-Lemeshow test showed good calibration (p = 0.515, X
conclusionsDiminished breath sounds, D-D levels, and LDH levels are independent risk factors for PB in children with adenoviral pneumonia. The developed nomogram demonstrates high predictive accuracy and good calibration, providing a valuable tool for early prediction and clinical decision-making. Future studies should validate this nomogram in larger and diverse populations.
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