Evidence map›Paper›PMID 40288954›Full record

ArticleCell proliferation2025

Mechanical Force Regulates the Paracrine Function of ADSCs to Promote the Adipose-Regenerating Effects of AAM by Regulating Angiogenesis and the Inflammatory Response.

Yining Wang, Luyu Zhang, Jiaxuan Liu, Yuchao Yang, Zhenyu Bi, Jun Ouyang

Abstract readLetter
In one paragraph

Article in Cell proliferation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yining WangGuangdong Provincial Key Laboratory of Digital Medicine and Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, National Key Discipline of Human Anatomy, Department of Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P. R. China.
Luyu ZhangYue Bei People's Hospital Postdoctoral Innovation Practice Base, Southern Medical University, Guangzhou, P. R. China.
Jiaxuan LiuGuangdong Provincial Key Laboratory of Digital Medicine and Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, National Key Discipline of Human Anatomy, Department of Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P. R. China.
Yuchao YangYue Bei People's Hospital Postdoctoral Innovation Practice Base, Southern Medical University, Guangzhou, P. R. China.ORCID https://orcid.org/0000-0003-0600-9615
Zhenyu BiGuangdong Provincial Key Laboratory of Digital Medicine and Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, National Key Discipline of Human Anatomy, Department of Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P. R. China.ORCID https://orcid.org/0009-0003-9872-7565
Jun OuyangGuangdong Provincial Key Laboratory of Digital Medicine and Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, National Key Discipline of Human Anatomy, Department of Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P. R. China.ORCID https://orcid.org/0000-0002-8475-3696

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2021A1515110440China Postdoctoral Science Foundation 2024M762753College Students' Innovative Entrepreneurial Training Plan Program 202412121323College Students' Innovative Entrepreneurial Training Plan Program S202412121190
6 · The paper itself

Abstract

Conditioned medium (CM), obtained by mechanical regulation of the paracrine activity of ADSCs, was fused with acellular adipose matrix (AAM) and methyl cellulose (MC) to synthesize a composite hydrogel which was grafted onto nude mice. The composite hydrogel could promote soft tissue regeneration by regulating the level of vascular regeneration and inflammation.

Indexed as

Adipose TissueInflammationNeovascularization, PhysiologicParacrine CommunicationRegenerationAngiogenesisAnimalsCells, CulturedCulture Media, ConditionedExtracellular MatrixHumansHydrogelsMiceMice, NudeTissue EngineeringCulture Media, ConditionedHydrogels

Identifiers

PMID40288954
PMCPMC12179550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.