Evidence map›Paper›PMID 40288887›Full record

ArticleBMJ quality & safety2026

Implementation of national guidelines on antenatal magnesium sulfate for neonatal neuroprotection: extended evaluation of the effectiveness and cost-effectiveness of the National PReCePT Programme in England.

Hannah B Edwards, Carlos Sillero-Rejon, Hugh McLeod, Elizabeth M Hill, Brent C Opmeer, Colin Peters, David Odd, Frank de Vocht, Karen Luyt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ quality & safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. International disparities in use of antenatal magnesium sulfate and antenatal steroids for the preterm baby.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hannah B EdwardsPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK hannah.edwards@bristol.ac.uk.ORCID http://orcid.org/0000-0002-1885-4771
Carlos Sillero-RejonPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0001-5502-9247
Hugh McLeodPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-2266-7303
Elizabeth M HillPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Brent C OpmeerNIHR ARC West, Bristol, UK.
Colin PetersNeonatology, Royal Hospital for Children, Glasgow, UK.
David OddPopulation Medicine, Cardiff University, Cardiff, UK.
Frank de VochtPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Karen LuytTranslational Health Sciences, University of Bristol Medical School, Bristol, Avon, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince 2015, the National Institute for Health and Care Excellence (NICE) guidelines have recommended antenatal magnesium sulfate (MgSO

methodsQuasi-experimental longitudinal study using data from the National Neonatal Research Database on babies born <30 weeks' gestation and admitted to a National Health Service neonatal unit. Primary outcome was the percentage of eligible mothers receiving MgSO

resultsMgSO

conclusionsThe PReCePT QI programme cost-effectively improved use of antenatal MgSO

Indexed as

Cerebral PalsyMagnesium SulfateNeuroprotective AgentsObstetric Labor, PrematurePrenatal CareCost-Benefit AnalysisCOVID-19EnglandFemaleHumansInfant, NewbornInfant, PrematureLongitudinal StudiesPractice Guidelines as TopicPregnancyPremature BirthMagnesium SulfateNeuroprotective AgentsCost-effectivenessEvidence-based medicineHealthcare quality improvementHealth services researchObstetrics and gynecology

Identifiers

PMID40288887
PMCPMC12911564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.