ArticleNeuroepidemiology2026
How Well Do Essential Tremor Patients Report whether or Not They Have Parkinson's Disease? Validity of Self-Report Data from a Large Cohort Study.
Article in Neuroepidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
BACKGROUND/
objectiveIn clinical and research studies in which one is dealing with essential tremor (ET) patients, the identification of related conditions, such as Parkinson's disease (PD), is important. A reasonable starting point is to directly ask the patient about their disease status. We are not aware of studies on the validity of ET patients' self-reports of PD (i.e., ETPD). Our aim was to assess the validity of a self-report of PD in this setting.
methodsET cases were enrolled in a prospective study. At each visit, they were asked, "Have you been diagnosed with Parkinson's disease?", a videotaped neurological examination was performed, and PD diagnoses (i.e., ETPD) were assigned by a senior movement disorders neurologist.
results291 ET cases underwent 899 study evaluations. Seven cases were diagnosed with ETPD. Summing data across all cases and all study evaluations, sensitivity = 56.3% and specificity = 98.1%. The positive predictive value of a report of PD was low (36.0%), whereas the negative predictive value of a report of no PD was high (99.2%).
conclusionsScreening, in general, can be a difficult process, but in the setting of ET and PD, the issues are particularly challenging. Our overarching goal is to fill a gap in knowledge and inform clinical researchers and treating physicians who are working with tremor populations. Although some information is garnered from asking ET patients whether they have been diagnosed with ETPD, the low sensitivity and low positive predictive values indicate that the value of self-reported PD diagnoses is limited.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.