Trial reportBMC neurology2025
Comparing face-to-face and online LSVT®LOUD speech training using LSVT®Coach in patients with Parkinson's disease: a pilot randomised controlled trial.
Trial report in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Digital Health Interventions on Motor Symptoms, Nonmotor Symptoms, and Quality of Life in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- [The impact of remote interactive voice therapy on patient adherence and treatment efficacy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLSVT®LOUD is an intensive speech therapy targeting voice amplitude, incorporating proprioceptive feedback and auditory-vocal self-monitoring, delivered through 16 one-hour sessions over a month with a high-effort approach. This study aimed to investigate preliminary effects of LSVT®LOUD teletherapy (LSVT®LOUD-tele) in comparison to traditional face-to-face LSVT®LOUD therapy (LSVT®LOUD-FTF) in people with PD and hypokinetic dysarthria, and to assess the usability of the LSVT®LOUD-tele software and the feasibility of a full-scale randomised controlled trial (RCT).
methodsUsing a pilot RCT, 20 people with PD and hypokinetic dysarthria were assigned to either LSVT®LOUD-tele or LSVT®LOUD-FTF, receiving 60-min sessions 4x/week for 4 weeks, along with home-based practice maintaining the same intensity and frequency in both conditions. Primary outcome was voice loudness (sound pressure levels [SPL]). Secondary outcomes included voice handicap, dysarthria-related QoL, HRQoL, and depression, assessed at baseline and post-intervention. The feasibility of conducting a full-scale RCT based on predetermined criteria (33% recruitment rate, 85% retention rate, 75% adherence rate, and high intervention safety) and the usability of the LSVT®LOUD-tele software were assessed post-intervention.
resultsNineteen participants completed the study (10 women). The LSVT®LOUD-FTF group showed improvements in vowel 'Ah' and 'high-pitched A' SPLs (Hedge's g = 1.416 and 0.826), while both groups showed increases in 'low-pitched A' and good quality loud voice SPLs (g = 0.148; g = 0.211). No changes were observed in everyday phrases SPL (g = 0.167) for either intervention, and both groups showed improvements in text reading (g = 0.436) and conversation SPLs (g = 0.345). Subjective voice handicap improved in both groups (eta squared [η
conclusionsBoth LSVT®LOUD-tele and LSVT®LOUD-FTF appear effective for people with PD and hypokinetic dysarthria, and the feasibility of a full-scale RCT was confirmed. Larger studies are needed to validate these findings.
trial registrationGerman Clinical Trials Register, DRKS00027825 . Registered on 13.01.2022.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.