Evidence map›Paper›PMID 40287662›Full record

ArticleBMC cardiovascular disorders2025

Temporal dynamics and clinical correlates of ischemic J waves in the early phase of acute myocardial infarction.

Huanhuan Hu, Lu Huang, Dewen Zhu, Mingwei Wang, Deye Yang, Hongyu Wang, Lina Chen

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huanhuan Hu *Division of Cardiology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, 313000, China.
Lu Huang *Division of Cardiology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou, 310015, China.
Dewen Zhu *Department of Cardiology, Shaoxing Central Hospital, NO.1 Huayu road, Shaoxing, 312000, China.
Mingwei WangDivision of Cardiology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou, 310015, China.
Deye YangDivision of Cardiology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou, 310015, China.
Hongyu WangVascular Medicine Center, Peking University Shougang Hospital, Beijing, 100144, China.
Lina ChenDepartment of Cardiology, Shaoxing Central Hospital, NO.1 Huayu road, Shaoxing, 312000, China. 13515751110@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to explore the temporal relationship between ischemic J waves and the progression of chest discomfort in patients experiencing acute myocardial infarction (AMI) during its earliest phase.

methodsA retrospective analysis was conducted on 466 AMI cases, each reporting chest discomfort lasting no longer than 4 h. The cohort was divided into four subgroups based on the duration of pain, and electrocardiographic (ECG) alterations were compared across these groups. Patients were categorized based on the presence or absence of J waves on their initial ECG, and a comprehensive analysis was performed comparing patient demographics, ECG characteristics, echocardiographic data, and coronary angiography results.

resultsJ waves were most prominent within the first hour of chest pain onset (p < 0.05). Patients with J waves had higher rates of ST-segment elevation myocardial infarction (STEMI) (91.4% vs. 50.4%, p < 0.001), lower heart rates (74.22 ± 9.49 vs. 80.43 ± 13.80 bpm, p < 0.001), elevated fasting glucose (8.50 ± 3.12 vs. 6.99 ± 2.20 mmol/L, p = 0.011), increased QT dispersion (90.48 ± 9.12 ms vs. 66.29 ± 11.84 ms, p < 0.001), and prolonged TpTe interval (the time interval from the peak of the T wave to its end point) (131.88 ± 19.81 ms vs. 96.99 ± 11.29 ms, p < 0.001). Multivariate analysis identified five independent factors linked to J wave presence: ST-segment elevation myocardial infarction (STEMI), reduced heart rate, elevated glucose, increased QT dispersion, and prolonged TpTe. J waves were also more frequent in patients with multi-vessel disease and right coronary artery involvement.

conclusionIschemic J waves are most detectable within the first hour of chest discomfort in AMI patients and are independently associated with STEMI, bradycardia, hyperglycemia, and specific ECG changes.

Indexed as

Angina PectorisElectrocardiographyHeart RateMyocardial InfarctionST Elevation Myocardial InfarctionAction PotentialsAgedCoronary AngiographyFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk FactorsTime FactorsAcute myocardial infarctionChest pain chronologyHyperacute phaseIschemic J wave phenomena

Identifiers

PMID40287662
PMCPMC12032808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.