ArticleBMC infectious diseases2025
Correlation between Escherichia coli infection during pregnancy and maternal-fetal outcomes: a retrospective analysis.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Article
- Comparative Effectiveness of Azithromycin versus Erythromycin for Latency Prolongation in Preterm Prelabor Rupture of Membranes < 34 Weeks of Gestation.International journal of women's health · 2026Article
- Research Progress on perinatalFrontiers in microbiology · 2026Review
- Application of microfluidic chip-based multiplex PCR in diagnosing reproductive tract pathogens among patients with premature rupture of membranes.Frontiers in cellular and infection microbiology · 2025Article
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Authors and funding
5 authors.
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Abstract
backgroundThere has been an increase in infections caused by Escherichia coli during pregnancy. E. coli is a major pathogen posing substantial risks to maternal and fetal health. However, knowledge of the impact of these infections on maternal and fetal outcomes is limited. This study aimed to investigate the high-risk factors related to Escherichia coli infection in pregnant women and associated maternal and fetal outcomes.
methodsThis retrospective analysis was performed using clinical data of pregnant women hospitalized between January 2020 and December 2022 for conditions such as premature rupture of membranes (PROM), threatened preterm labor, threatened miscarriage, and fever, all of whom underwent microbiological testing. Patients were categorized into E. coli or non-E. coli infection groups based on bacterial culture results. High-risk factors for E. coli infection and associated pregnancy outcomes were assessed.
resultsMicrobiological analysis of 7,213 clinical specimens revealed 925 positive cases, with E. coli infection accounting for 202 cases. Primiparity (odds ratio = 2.981, 95% CI 1.877-4.709, P < 0.001) and a pre-pregnancy body mass index of ≥ 24 kg/m
conclusionsThe prevalence of E. coli is high among pregnant women. This observational study suggests an association between maternal E. coli infection and adverse pregnancy outcomes in high-risk populations.
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