Evidence map›Paper›PMID 40287641›Full record

SynthesisBMC pregnancy and childbirth2025

Pharmacological pain relief and women´s birth experience: a systematic review.

Malin Ugarph Edfeldt, Hanne Gustavsson, Karin Hildén, Yang Cao, Helena Backman

Abstract readSystematic Review
In one paragraph

Synthesis in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Malin Ugarph EdfeldtSchool of Medical Sciences, Örebro University, Örebro, SE, S-701 82, Sweden. malin.ugarph-edfeldt@oru.se.
Hanne GustavssonCapio Health Center Ringen, Stockholm, SE, S-118 60, Sweden.
Karin HildénSchool of Medical Sciences, Örebro University, Örebro, SE, S-701 82, Sweden.
Yang CaoClinical Epidemiology and Biostatistics, School of Medical Sciences, Orebro University, Orebro, SE, S-701 82, Sweden.
Helena BackmanSchool of Medical Sciences, Örebro University, Örebro, SE, S-701 82, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is increasing interest in health care systems worldwide for maternal satisfaction with childbirth experience. The World Health Organisation (WHO) launched a recommendation 2018 regarding women's right to equal and fair intrapartum care, where the importance of pharmacological pain relief was highlighted. Our objective with this systematic review was to summarize and assess the current knowledge regarding the impact of obstetric pharmacological pain relief on maternal satisfaction with childbirth.

methodsThe databases Pub Med, Cochrane, EMBASE and CINAHL were searched for studies in the English language published after 1998 that investigated the effect of pharmacological pain relief on women´s birth experience after vaginal delivery. Studies reporting assessments of subjective satisfaction with childbirth in women planned for vaginal delivery were selected. The results were summarized narratively. For studies where comparable association measures were available, forest plots are presented. Due to heterogeneity of research questions and indirectness of measuring instruments, no meta-analyses were performed.

resultsA total of 15,136 women were included from 18 studies. Two randomized controlled studies, nine cohort studies, six cross-sectional studies and one case control study, all had a moderate or high risk of bias. The studies used inconsistent methods to measure outcomes; therefore, no conclusion could be drawn regarding a possible correlation between pharmacological pain relief and overall birth experience.

conclusionsThis systematic review could not show a correlation between pharmacological pain relief and women´s experiences of childbirth, mainly due to large heterogeneity between studies. To evaluate pain relief during labour and improve women´s childbirth experiences, high-quality research is warranted.

trial registrationThe study was registered in PROSPERO (prospective register of systematic reviews) 18 Dec 2018 (ID 116744).

Indexed as

Analgesia, ObstetricalDelivery, ObstetricLabor PainPain ManagementParturitionPatient SatisfactionFemaleHumansPregnancyBirth experienceChildbirth satisfactionLaborPharmacological pain reliefPregnancy

Identifiers

PMID40287641
PMCPMC12032825

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.