Evidence map›Paper›PMID 40287563›Full record

ArticleScientific reports2025

The effects of LED Spectra on synthesis of antiparasitic bioactive compound in Eurycoma longifolia hairy root culture against Blastocystis Sp.

Mahmoud Ali Khalaf Abushattal, Sani Sale, Sreeramanan Subramaniam, Mohamad Nurul Azmi Mohamad Taib, Arutchelvan Rajamanikam, Farah Haziqa Meor Termizi, Nor Hasnida Hassan, Mohamad Fadhli Mad' Atari

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahmoud Ali Khalaf AbushattalSchool of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown, 11800, Penang, Malaysia.
Sani SaleSchool of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown, 11800, Penang, Malaysia.
Sreeramanan SubramaniamSchool of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown, 11800, Penang, Malaysia.
Mohamad Nurul Azmi Mohamad TaibSchool of Chemical Sciences, Universiti Sains Malaysia (USM), Georgetown, 11800, Penang, Malaysia.
Arutchelvan RajamanikamDepartment of Parasitology, Faculty of Medicine, Universiti of Malaya, Kuala Lumpur, 50603, Malaysia. arun04@um.edu.my.
Farah Haziqa Meor TermiziSchool of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown, 11800, Penang, Malaysia.
Nor Hasnida HassanForest Biotechnology Division, Forest Research Institute Malaysia (FRIM), Kepong, 52109, Selangor, Malaysia.
Mohamad Fadhli Mad' AtariSchool of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown, 11800, Penang, Malaysia. madatari@usm.my.

Funding

Ministry of Higher Education, Malaysia FRGS/1/2020/STG03/USM/02/21
6 · The paper itself

Abstract

Eurycoma longifolia (also known as Tongkat Ali) is one of the valuable medicinal plants frequently used as traditional medicine in Malaysia. Its alkaloids and quassinoids reportedly confers antiparasitic activities. The effect of different Light Emitting Diode (LED) spectra treatments on E. longifolia hairy root cultures (ELHRCs) on alkaloid synthesis remains unexplored and its consequent antiparasitic effect on Blastocystis sp., a common intestinal protozoan parasite, is still unknown. In this study, the ELHRCs were irradiated to white, blue, red, blue plus red (1:1) and mint green LED illumination in vitro. The variation of alkaloids was assessed by using High-Performance Liquid Chromatography (HPLC) and employed to quantify 9-hydroxycanthin-6-one and 9-methoxycanthin-6-one. Subsequently, antiparasitic effect on Blastocystis sp. was assessed in in vitro parasite culture and the minimum inhibitory concentration (MIC

Indexed as

Antiparasitic AgentsBlastocystisEurycomaPlant RootsAlkaloidsPlant ExtractsAlkaloidsAntiparasitic AgentsPlant Extracts9-methoxycanthin-6-oneAnti-protozoal activity.Hairy rootsLED spectrumTongkat Ali

Identifiers

PMID40287563
PMCPMC12033243

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.