ArticleScientific reports2025
AI-based analysis of surgical outcomes in vitrectomy with and without cystotomy for refractory cystoid diabetic macular edema.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Artificial Intelligence in Vitreoretinal Surgery: A Systematic Review of Current Applications and Future Directions.Ophthalmology and therapy · 2026Review
- Differences in Artificial Intelligence-Based Macular Fluid Parameters Between Clinical Stages of Diabetic Macular Edema and Their Relationship with Visual Acuity.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to compare surgical outcomes in vitrectomy with and without cystotomy for refractory cystoid diabetic macular edema (DME). This study enrolled 35 eyes of 29 patients who underwent vitrectomy for refractory DME. The eyes were divided into 2 groups, those undergoing vitrectomy with cystotomy (cystotomy group) (n = 8) and vitrectomy with internal limiting membrane (ILM) peeling only (ILM peeling group) (n = 27). The endpoints were central retinal thickness (CRT), best-corrected visual acuity (BCVA), macular fluid (MF) area. The MF area was determined and measured using a semantic segmentation model "Hokkaido University MF segmentation model" and subdivided into inner MF (IMF) area bounded by the inner nuclear layer (INL), and outer MF (OMF) area between the outer border of INL and ellipsoid zone. The cystotomy group showed a significant reduction in CRT at 1 month postoperatively compared to the ILM peeling group (P < 0.05). The cystotomy group preserved BCVA at 6 months postoperatively compared to preoperatively. There was a significant difference between the cystotomy and the ILM peeling groups in the reduction of the OMF area at 1 month postoperatively (P < 0.01). Cystotomy for refractory DME was more effective in reducing the OMF area.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.