Evidence map›Paper›PMID 40287428›Full record

ArticleNPJ systems biology and applications2025

Biochemical implementation of acceleration sensing and PIDA control.

Emmanouil Alexis, Sebastián Espinel-Ríos, Ioannis G Kevrekidis, José L Avalos

Abstract read
In one paragraph

Article in NPJ systems biology and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emmanouil AlexisDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA. ea2063@princeton.edu.
Sebastián Espinel-RíosDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA.
Ioannis G KevrekidisDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.
José L AvalosDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA.

Funding

U.S. DOE-BER DE-SC0022155U.S. NSF MCB-2300239
6 · The paper itself

Abstract

This work introduces a realization of a proportional-integral-derivative-acceleration control scheme as a chemical reaction network governed by mass action kinetics. A central feature of this architecture is a speed and acceleration biosensing mechanism integrated into a feedback configuration. Our control scheme provides enhanced dynamic performance and robust steady-state tracking. In addition to our theoretical analysis, this is practically highlighted in-silico in both the deterministic and stochastic settings.

Indexed as

Biosensing TechniquesAlgorithmsComputer SimulationFeedbackKineticsStochastic Processes

Identifiers

PMID40287428
PMCPMC12033284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.