ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2025
Characterization of Patients With Symptoms of Gastroparesis Having Frequent Emergency Department Visits and Hospitalizations.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Development and validation of a rapid 15-minute gastric ultrasound protocol for suspected gastroparesis: a prospective diagnostic accuracy study.Annals of medicine · 2026Article
- Abdominal Pain Sensitization Connected With Upper but Not Lower Abdominal Pain in Adults With Gastroparesis.Neurogastroenterology and motility · 2026Observational
- Glucagon-like Peptide-1 Receptor Agonist Therapy and Risk of Pulmonary and Systemic Infections in Diabetic Gastroparesis: A Propensity-Matched Cohort Study.Advances in respiratory medicine · 2026Article
- Exploring Clinical Similarities and Distinctions Between Gastroparesis and Functional Dyspepsia: A Propensity-Matched Cohort Study.Neurogastroenterology and motility · 2026Observational
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Authors and funding
19 authors.
Funding
Abstract
BACKGROUND &
aimsPatients with gastroparesis (Gp) can be high users of the medical system. In this study, we characterized patients with Gp symptoms who had frequent emergency department (ED) visits and hospitalizations.
methodsPatients with symptoms of Gp underwent history and physical examination, gastric emptying scintigraphy (GES), and questionnaires capturing number of ED visits and hospitalizations over the prior year, GI symptoms (Patient Assessment of Upper GI Symptoms [PAGI-SYM]), anxiety and depression [Hospital Anxiety and Depression Scale (HADS)], somatization [Patient Health Questionnaire (PHQ-15)], and quality of life (SF-36v2 and Patient Assessment of Upper GastroIntestinal Disorders-Quality of Life [PAGI-QOL]).
resultsOf 406 patients with symptoms of Gp (294; 72.4%) had delayed gastric emptying (33% diabetic, 61% idiopathic, 6% postfundoplication), 159 patients (39%) had prior ED visits. Baseline characteristics that were independently associated with ED visits over the prior year included younger age, Black race, lower income, higher gastric retention on GES at 4 hours, antiemetic medication use, cannabis use, jejunostomy tube presence, and higher nausea/vomiting scores. Ninety-two patients (23%) had hospitalizations due to symptoms of Gp over the prior year. The most frequent reasons for hospitalizations included nausea (83%), vomiting (78%), abdominal pain (70%), and dehydration (59%). Baseline characteristics that were independently associated with increased hospitalizations were younger age, Black race, lower income, diabetic etiology, greater 4-hour gastric retention, prokinetic use, cannabis use, jejunostomy tube presence, higher nausea/vomiting scores, and higher depression scores.
conclusionsOur study of patients with symptoms of Gp revealed a sizeable subset have had Gp-related ED visits and hospitalizations over the past year. Several factors related to etiology, GE delay, GI symptom severity, depression severity, race, and lower income were associated with ED visits and hospitalizations. CLINICALTRIALS: gov Identifier: N3CT01696747.
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