Evidence map›Paper›PMID 40286728›Full record

ArticleClinics (Sao Paulo, Brazil)2025

Effect of combined training on the cardiorespiratory, muscle system and body composition in employees at a tertiary hospital after mild to moderate intensity COVID 19.

Marcus Vinicius Grecco, Alexandre Moura Dos Santos, JúliaMaria D'Andrea Greve, Angélica Castilho Alonso, Mara Silvia Afonso, Juliana Cristina de Sousa, Marília Simões Lopes Quintana, José Maria Soares-Junior, Edmund Chada Baracat, Guilherme Carlos Brech and 1 more

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marcus Vinicius GreccoLaboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; Sports Medicine Division, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; FIFA Medical Centre of Excellence, São Paulo, SP, Brazil.
Alexandre Moura Dos SantosDepartment of Rheumatology at Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
JúliaMaria D'Andrea GreveLaboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; Sports Medicine Division, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; FIFA Medical Centre of Excellence, São Paulo, SP, Brazil.
Angélica Castilho AlonsoGraduate Program in Aging Sciences, Universidade São Judas Tadeu (USJT), São Paulo, SP, Brazil.
Mara Silvia AfonsoLaboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; Sports Medicine Division, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; FIFA Medical Centre of Excellence, São Paulo, SP, Brazil.
Juliana Cristina de SousaLaboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; Sports Medicine Division, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; FIFA Medical Centre of Excellence, São Paulo, SP, Brazil.
Marília Simões Lopes QuintanaLaboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil.
José Maria Soares-JuniorDepartment of Obstetrics and Gynecology, Gynecology Discipline, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Edmund Chada BaracatDepartment of Obstetrics and Gynecology, Gynecology Discipline, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Guilherme Carlos BrechGraduate Program in Aging Sciences, Universidade São Judas Tadeu (USJT), São Paulo, SP, Brazil. Electronic address: guibrech@gmail.com.
Paulo Roberto Santos SilvaLaboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; Sports Medicine Division, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; FIFA Medical Centre of Excellence, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo verify the effect of 12 weeks of Combined Training (CT) in patients suffering from COVID-19 of mild to moderate intensity.

methods69 participants diagnosed with mild to moderate COVID-19 were evaluated, with shortness of breath as the main symptom. All of them were sent by the Centro de Atendimento ao Funcionário do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (CEAC-HCFMUSP). The sample was divided into three groups: Group 1 (G1) - 26 patients diagnosed with COVID-19 evaluated before and after combined training together with nutritional guidance. Group 2 (G2) - 21 patients diagnosed with COVID-19 were evaluated before and after 12 weeks. Patients in G2 (control) did not participate in the protocol but were instructed to train outside the hospital and did not receive nutritional guidance. Group 3 (G3) - 22 patients diagnosed with COVID-19 were evaluated before and after combined training along with nutritional monitoring and post-workout whey protein supplementation throughout the duration of the protocol.

resultsThe three groups did not have significant statistical differences when compared to each other, but there was significant intragroup improvement in the analyzed variables. There was an improvement in cardiorespiratory, metabolic, and muscular fitness. Furthermore, late symptoms of the disease were reduced at the end of the program.

conclusionThe results of the dependent variables analyzed were significant within groups, CT was an efficient training model in improving the patient's general condition (fatigue and dyspnea) when training was controlled with supervision.

Indexed as

Body CompositionCardiorespiratory FitnessCOVID-19Exercise TherapyAdultDyspneaFemaleHumansMaleMiddle AgedSARS-CoV-2Severity of Illness IndexTertiary Care CentersTreatment OutcomeCardiopulmonary exercise testingcombined trainingCOVID-19ErgospirometryRehabilitation

Identifiers

PMID40286728
PMCPMC12060513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.