Evidence map›Paper›PMID 40286280›Full record

ArticleEpilepsia2025

Cognitive screening informs referrals for neuropsychological evaluation in children with epilepsy.

Kristina E Patrick, Allison N Shields, Holly A Dustin, Anup D Patel, Kelly McNally

Abstract read
In one paragraph

Article in Epilepsia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristina E PatrickDepartment of Neuropsychology, Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0003-1626-7474
Allison N ShieldsDepartment of Neurosciences, Seattle Children's Hospital, Seattle, Washington, USA.
Holly A DustinDepartment of Neuropsychology, Nationwide Children's Hospital, Columbus, Ohio, USA.
Anup D PatelDivision of Neurology, Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-9313-1541
Kelly McNallyDepartment of Neuropsychology, Nationwide Children's Hospital, Columbus, Ohio, USA.

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUM1TR004548 · NCATS · OHIO STATE UNIVERSITY · PI CYNTHIA A GERHARDT, JULIE A. JOHNSON · 2023 to 2026
$22.0M
Nationwide Children's HospitalNCATS NIH HHS UM1 TR004548NCATS NIH HHS UM1TR004548The Ohio State University Clinical and Translational Science Institute
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the effectiveness of current neuropsychology referral methods for children with epilepsy and develop data-informed recommendations for use of performance-based cognitive screening measures to improve these processes.

methodsChildren with epilepsy who had been referred to neuropsychology (n = 51) or had never been referred (n = 34) completed four brief tablet-based screening tests from the National Institutes of Health Toolbox Cognition Battery along with a comprehensive neuropsychological test battery. Demographics, medical information, and parent questionnaires were gathered.

resultsMean performance on the neuropsychological test battery was worse in the referral group (p = .008, d = .52), but percentage of patients who presented with cognitive impairment (at least two scores 1.5 SD below the mean) did not differ. Demographics did not predict performance on the comprehensive neurocognitive battery (p = .46, SIGNIFICANCE: Brief and easy to administer performance-based cognitive screening may add value and reduce bias when making decisions about neuropsychology referrals for children with epilepsy. An ideal clinical model could include neuropsychology consultation with chart review, clinical interview, questionnaires, and brief cognitive screening to inform referrals for more comprehensive evaluation. In settings where this is not possible, cognitive screening may be a useful and minimally resource-intensive method for informing referral decisions.

Indexed as

Cognitive DysfunctionEpilepsyNeuropsychological TestsReferral and ConsultationAdolescentChildChild, PreschoolFemaleHumansMaleSurveys and QuestionnairesDimensional Change Card SortFlankerNIH ToolboxPattern Comparison TestPicture Vocabulary Test

Identifiers

PMID40286280
PMCPMC12353113

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.