Evidence map›Paper›PMID 40286237›Full record

ArticleMolecules (Basel, Switzerland)2025

Gold(III) Complexes with 2-(1-Ethylbenzyl)pyridine as Promising Antimicrobial and Antitumor Agents.

Antonio Zucca, Bruna Canu, Maria I Pilo, Sergio Stoccoro, Giacomo Senzacqua, Sara Fais, Giuseppina Pichiri, Alessandra Scano

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonio ZuccaDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.ORCID 0000-0003-4423-9382
Bruna CanuDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
Maria I PiloDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.ORCID 0000-0003-4810-1102
Sergio StoccoroDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.ORCID 0000-0003-3389-7443
Giacomo SenzacquaDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
Sara FaisDepartment of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.
Giuseppina PichiriDepartment of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0001-8700-8854
Alessandra ScanoDepartment of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-4385-8002

Funding

European Union - Next generationEU, code MUR (Italian Ministry for University and Research) P2022PZ8JE
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is one of the most urgent public health problems worldwide; multidrug resistance (MDR) is also of concern. In an effort to find new classes of antibiotics, recent studies have found that coordination compounds of noble metals show promising biological effects both in vitro and in vivo, deserving attention as a new class of possible antimicrobial agents. Metal ions in biological systems can essentially have two roles: structural or functional. In the former, the metal ion serves to stabilize structures, especially proteins, while in the latter, the metal is involved in bio-site reactivity (essentially in metallo-enzymes). Two new complexes with 2-(1-ethyl-benzyl)pyridine (py

Indexed as

Anti-Infective AgentsAntineoplastic AgentsCoordination ComplexesGoldPyridinesAnti-Bacterial AgentsBiofilmsGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsCoordination ComplexesGoldPyridinesantimicrobial complexesGold(III) cyclometalated compoundslaboratory medicinenitrogen ligands

Identifiers

PMID40286237
PMCPMC11990560

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.