ReviewMolecules (Basel, Switzerland)2025
History of Organophosphorus Compounds in the Context of Their Use as Chemical Warfare Agents.
Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Kinetics of the Gas-Phase Reaction of Hydroxyl Radicals with Trimethyl Phosphite (TMPi) over the 295-735 K Temperature Range.The journal of physical chemistry. A · 2026Article
- Antibacterial Activity of α-Sulfamidophosphonate Derivatives and Their In Silico Assessment as Dihydropteroate Synthase Binders.Chemistry & biodiversity · 2026Article
- Computational Chemistry and Toxicology of Phosphonate Esters of Alkyl Acetoacetates, an Unexplored Class of V-Agents.Current issues in molecular biology · 2026Article
- Chemical neighborhood exploration for substrate discovery in biocatalysis.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genomic Impacts of Biological Exposures.Journal of developmental biology · 2026Review
- Article
- Organophosphate Chemical Nerve Agents, Oxidative Stress, and NADPH Oxidase Inhibitors: An Overview.International journal of molecular sciences · 2025Review
- Thiophosphoryl-PMMH Dendrimers for Potential Detection and Remediation of CBRN Contamination: Selected Studies and General Guidelines and Procedures.Materials (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This is a broad look at the history of phosphorus-from the element through its inorganic and organic compounds to the applications of organophosphates. In addition to commercial and peaceful applications, they were used as chemical warfare agents (CWA), both in military operations and for terrorist purposes. This article attempts to provide a concise history of their development and application in this shameful role. The origin of the chemistry of phosphorus compounds to obtain precursors for the production of CWA is presented. Rapid progress in organophosphorus chemistry in the second half of the 20th century is also described. A broad overview of chemical structures is presented, including lesser-known representatives. The mode of action and the associated toxicity of organophosphorus compounds are briefly mentioned. The Chemical Weapons Convention (CWC) schedules and their changes during their validity are indicated. They are also demonstrated to be used in proficiency tests organised by the Organization for the Prohibition of Chemical Weapons (OPCW). Organophosphates called "Novichok agents", classified as fourth-generation chemical warfare agents, are also briefly discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.