Evidence map›Paper›PMID 40286149›Full record

ArticleMolecules (Basel, Switzerland)2025

Mechanochemically-Activated Solid-State Synthesis of Borate-Substituted Tricalcium Phosphate: Evaluation of Biocompatibility and Antimicrobial Performance.

Daniil O Golubchikov, Inna V Fadeeva, Alexander V Knot'ko, Iliya A Kostykov, Tatiana K Slonskaya, Katia Barbaro, Alessia Zepparoni, Marco Fosca, Iulian V Antoniac, Julietta V Rau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniil O GolubchikovChemistry Department, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.ORCID 0000-0001-8488-6387
Inna V FadeevaA.A. Baikov Institute of Metallurgy and Material Science, Russian Academy of Sciences, Leninsky 49, 119334 Moscow, Russia.ORCID 0000-0003-2719-7133
Alexander V Knot'koChemistry Department, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Iliya A KostykovChemistry Department, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.ORCID 0000-0002-3435-2878
Tatiana K SlonskayaDepartment of Analytical, Physical and Colloid Chemistry, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Trubetskaya 8, build. 2, 119048 Moscow, Russia.
Katia BarbaroIstituto Zooprofilattico Sperimentale Lazio e Toscana "M. Aleandri", Via Appia Nuova 14111, 00178 Rome, Italy.ORCID 0000-0001-9830-996X
Alessia ZepparoniIstituto Zooprofilattico Sperimentale Lazio e Toscana "M. Aleandri", Via Appia Nuova 14111, 00178 Rome, Italy.
Marco FoscaIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche, ISM-CNR, Via del Fosso del Cavaliere 100, 00133 Rome, Italy.ORCID 0000-0003-0962-8083
Iulian V AntoniacFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, District 6, RO-060042 Bucharest, Romania.ORCID 0000-0003-0112-3494
Julietta V RauDepartment of Analytical, Physical and Colloid Chemistry, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Trubetskaya 8, build. 2, 119048 Moscow, Russia.ORCID 0000-0002-7953-1853

Funding

Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana 02/23 RCMinistry of Science and Education of the Russian Federation 075-00319-25-00
6 · The paper itself

Abstract

Current research in bone tissue engineering is focused not only on basic parameters of the materials, such as biocompatibility and degradation rate but also on intrinsic osteogenic and antimicrobial properties, essential to provide a rapid tissue regeneration without negative effects due to periprosthetic infections, that may result in revision surgeries. One of the major strategies to enhance the osteogenic and antimicrobial performance of calcium phosphates is the ionic substitution, in particular, with magnesium and borates. In this study, we focused on the synthesis of boron-substituted tricalcium phosphate (B-TCP) with a target of 5 mol.% substitution via the solid-state synthesis with mechano-activation. Synthesis from raw precursors, without the preliminary brushite wet precipitation, led to the primary phase of β-TCP, which was proved by the XRD analysis. According to the IR-spectroscopy and

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBiocompatible MaterialsBoratesCalcium PhosphatesEnterococcus faecalisEscherichia coliHumansMaterials TestingMesenchymal Stem CellsMicrobial Sensitivity TestsOsteogenesisAnti-Bacterial AgentsAnti-Infective Agentsbeta-tricalcium phosphateBiocompatible MaterialsBoratesCalcium Phosphatestricalcium phosphateantimicrobial propertiesbiocompatibilitybone tissue engineeringborate-substituted tricalcium phosphatetricalcium phosphate ceramics

Identifiers

PMID40286149
PMCPMC11990300

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.