Evidence map›Paper›PMID 40286078›Full record

ReviewMolecules (Basel, Switzerland)2025

Biological Activity of Monoterpene-Based Scaffolds: A Natural Toolbox for Drug Discovery.

Jarosław Mołdoch, Monika Agacka-Mołdoch, Grzegorz Jóźwiak, Karolina Wojtunik-Kulesza

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Whole-Genome Sequence Dataset ofMolecules (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jarosław MołdochDepartment of Biochemistry and Crop Quality, Institute of Soil Science and Plant Cultivation, State Research Institute, 24-100 Puławy, Poland.ORCID 0000-0002-8844-3986
Monika Agacka-MołdochDepartment of Plant Breeding and Biotechnology, Institute of Soil Science and Plant Cultivation, State Research Institute, Czartoryskich 8, 24-100 Puławy, Poland.ORCID 0000-0001-9373-6129
Grzegorz JóźwiakDepartment of Inorganic Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland.
Karolina Wojtunik-KuleszaDepartment of Inorganic Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland.ORCID 0000-0002-6541-8817

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most common strategies used in drug design is the molecular scaffold approach, which combines traditional medicine based on natural active compounds derived from plants with modern synthetic drug development. Designing new compounds based on natural skeletons enables extensive modifications of both bioavailability and biological activity. An excellent example of a natural molecular scaffold is the monoterpenes group, which serves as a core structure for building more complex molecules by attaching various chemical groups. Their ability to interact with biological targets, combined with structural versatility, makes them promising molecular scaffolds in pharmaceutical research and green chemistry applications. This review paper focuses on selected monoterpenes (carvacrol, carvone, citral, menthol, menthone,

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsAntiviral AgentsDrug DesignMonoterpenesNeuroprotective AgentsAnimalsHumansAnti-Bacterial AgentsAntineoplastic AgentsAntiviral AgentsMonoterpenesNeuroprotective Agentscarvacrolcarvonecitralmentholmenthonemolecular scaffoldmonoterpenesthymolverbenoneβ-pinene

Identifiers

PMID40286078
PMCPMC11990750

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.