Evidence map›Paper›PMID 40286031›Full record

ArticleMolecules (Basel, Switzerland)2025

The Effect of Polyethylene Terephthalate Nanoplastics on Amyloid-β Peptide Fibrillation.

Narmin Bashirova, Franziska Schölzel, Dominik Hornig, Holger A Scheidt, Martin Krueger, Georgeta Salvan, Daniel Huster, Joerg Matysik, A Alia

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Narmin BashirovaInstitute of Medical Physics and Biophysics, Leipzig University, D-04107 Leipzig, Germany.ORCID 0009-0009-7490-4225
Franziska SchölzelInstitute of Physics, Chemnitz University of Technology, D-09126 Chemnitz, Germany.ORCID 0009-0001-7489-863X
Dominik HornigCenter for Materials, Architectures and Integration of Nanomembranes, Chemnitz University of Technology, D-09126 Chemnitz, Germany.ORCID 0009-0008-9014-3449
Holger A ScheidtInstitute of Medical Physics and Biophysics, Leipzig University, D-04107 Leipzig, Germany.ORCID 0000-0001-9935-8229
Martin KruegerInstitute of Anatomy, Leipzig University, D-04107 Leipzig, Germany.
Georgeta SalvanInstitute of Physics, Chemnitz University of Technology, D-09126 Chemnitz, Germany.ORCID 0000-0002-2565-9675
Daniel HusterInstitute of Medical Physics and Biophysics, Leipzig University, D-04107 Leipzig, Germany.ORCID 0000-0002-3273-0943
Joerg MatysikInstitute of Analytical Chemistry, Leipzig University, D-04103 Leipzig, Germany.ORCID 0000-0002-7800-7443
A AliaInstitute of Medical Physics and Biophysics, Leipzig University, D-04107 Leipzig, Germany.ORCID 0000-0002-4900-9749

Funding

Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) - TRR-386 (HYP*MOL) - A1& B3 (514664767)
6 · The paper itself

Abstract

Exposure of organisms to nanoplastics (NPs) is inevitable given their global abundance and environmental persistence. Polyethylene terephthalate (PET) is a common plastic used in a wide range of products, including clothing and food and beverage packaging. Recent studies suggest that NPs can cross the blood-brain barrier and cause potential neurotoxicity. It is widely known that aggregation of amyloid beta (Aβ) peptides in the brain is a pathological hallmark of Alzheimer's disease (AD). While the impact of nanoplastics such as polystyrene (PS) on amyloid aggregation has been studied, the effects of PET NPs remain unexplored. In this study, we examined the effect of PET NPs of different sizes (PET

Indexed as

Amyloid beta-PeptidesMicroplasticsNanoparticlesPeptide FragmentsPolyethylene TerephthalatesAmyloidHumansParticle SizeProtein AggregatesAmyloidAmyloid beta-PeptidesMicroplasticsPeptide FragmentsPolyethylene TerephthalatesProtein Aggregatesamyloid βfibrillationnanoplasticspolyethylene terephthalate

Identifiers

PMID40286031
PMCPMC11990616

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.