ArticleMolecules (Basel, Switzerland)2025
Phenolics as Active Ingredients in Skincare Products: A Myth or Reality?
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Unlocking the Potential ofFoods (Basel, Switzerland) · 2026Review
- From Waste to Beauty: Agri-Food By-Products as Sources of Antioxidant Compounds for Cosmeceutical Applications.Antioxidants (Basel, Switzerland) · 2026Review
- Valorization ofPlants (Basel, Switzerland) · 2026Article
- Review
- Mechanistic Elucidation of the Anti-Ageing Effects ofFoods (Basel, Switzerland) · 2025Article
- Photoprotective Effects of Quercetin and Hesperidin in Polymorphous Light Eruption: A Comparative Study with Alpha-Glucosylrutin.Current issues in molecular biology · 2025Article
- Skin Photoaging and the Biological Mechanism of the Protective Effects of Hesperidin and Derived Molecules.Antioxidants (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Phenolic compounds, with their diverse biological activities, are widely explored as cosmetic ingredients with photoprotective, antioxidant, anti-inflammatory, and anti-hyperpigmentation properties, offering a multitargeted approach to combat photo-induced skin aging. The study analyzed 1299 cosmetic products from 2021 to 2024 to understand the market impact of phenolic compounds and their mechanism of action against photo-induced skin damage. A total of 28 active phenolic compounds were identified and the prevalence of phenolics was 13.2% in anti-aging products, 5.2% in sunscreens and 4.8% in aftersun products. Bakuchiol and polyphenols, such as resveratrol, chrysin, and hesperidin methyl chalcone, were found in anti-aging products. Sunscreens and aftersun products were counted with ferulic and caffeic acids, and salicylic acid, respectively. Antioxidant activity was found to be the primary mechanism of action of phenolic compounds by scavenging reactive species, thus mitigating oxidative stress. Ferulic and caffeic acids, chrysin, and glucosylrutin can also absorb UV radiation, acting preventively against solar-induced skin damage. This study provides insights into the limited use of phenolic compounds in commercial cosmetics, despite their diverse biological activities, and suggests potential barriers to wider use in skin and sun care products.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.