Evidence map›Paper›PMID 40285954›Full record

ArticleClinical oral investigations2025

In vivo periodontal ultrasound imaging via a hockey-stick transducer and comparison to periodontal probing: a proof-of-concept study.

Lei Fu, Jason J Chang, Khalid Al Hezaimi, Lekshimi Sasi, Suhel Khan, Baiyan Qi, Casey Chen, Jesse V Jokerst

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei FuAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, La Jolla, San Diego, CA, 92093, USA.
Jason J ChangHerman Ostrow School of Dentistry, University of Southern California, 925 West 34th Street, Los Angeles, CA, USA.
Khalid Al HezaimiHerman Ostrow School of Dentistry, University of Southern California, 925 West 34th Street, Los Angeles, CA, USA.
Lekshimi SasiAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, La Jolla, San Diego, CA, 92093, USA.
Suhel KhanAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, La Jolla, San Diego, CA, 92093, USA.
Baiyan QiMaterial Science and Engineering Program, University of California, La Jolla, San Diego, CA, 92093, USA.
Casey ChenHerman Ostrow School of Dentistry, University of Southern California, 925 West 34th Street, Los Angeles, CA, USA.
Jesse V JokerstAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, La Jolla, San Diego, CA, 92093, USA. jjokerst@ucsd.edu.

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
A Miniaturized and High-frequency Acoustic Imaging System for Oral Health and Diseases of the Head and NeckR01DE031307 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Vincent Jokerst · 2022 to 2026
$3.1M
NCATS NIH HHS UL1 TR001442NIDCR NIH HHS R01 DE031307NIH HHS UL1 TR001442.
6 · The paper itself

Abstract

objectiveThe objective of this study is to evaluate a compact ultrasound transducer to image anatomical biomarkers for periodontal diagnosis of teeth, including difficult-to-reach posterior teeth. MATERIALS AND

methodsA 9-MHz hockey-stick transducer was used to image 53 premolars, 30 molars, and 79 incisors and canines from 13 subjects. The alveolar bone crest (ABC), cementoenamel junction (CEJ), and gingival margin (GM) were identified by ultrasound imaging. The image-based distances between these anatomic landmarks were measured for iABC (ABC to CEJ), iGR (GM to CEJ) and iGH (ABC to GM). The measurements were compared to corresponding parameters obtained from clinical examination. The measurements were also used to assess periodontal health and were compared with clinical diagnosis.

resultsThe average iGR measurements were - 1.12 mm (i.e., 1.12 mm above the CEJ) for gingivitis and Stage I periodontitis, and - 0.56 mm for Stage III periodontitis, demonstrating a significant increase in gingival recession in patients with severe periodontitis (Student t-test, unpaired, two-tailed, p < 0.0001). The iGH measurements distinguished gingivitis, Stage I periodontitis group, and the Stage III periodontitis group (unpaired, two-tailed t-test, p < 0.05 for PPD, and p = 0.05 for iGH).

conclusionNon-invasive periodontal ultrasound imaging can be used to stratify subjects with differing periodontal disease severity. The clinical parameters obtained from ultrasound imaging with the hockey-stick transducer are reproducible. CLINICAL RELEVANCE: The compact ultrasound transducer can be used as a screening tool for patients affected by periodontitis for clinical examination and treatment.

Indexed as

PeriodontitisTransducersAdultEquipment DesignFemaleHumansMaleMiddle AgedProof of Concept StudyUltrasonographyPeriodontal probingPeriodontitisUltrasound imaging

Identifiers

PMID40285954
PMCPMC12033097

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.