Evidence map›Paper›PMID 40285871›Full record

ReviewNeuroradiology2025

Styloid process-related internal carotid artery dissection: extensive literature review of diagnosis, treatment and outcomes (exemplified with a single-center case series).

Tomas Klail, Ludwig Sachs, Leonidas D Panos, Oliver Y Urban, Teresa Siller, Sara Pilgram-Pastor, Roland Giger, Martin Müller, Franca Wagner

Abstract readReview
In one paragraph

Review in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomas KlailUniversity Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland. tomas.klail@team-radiologie.ch.ORCID http://orcid.org/0000-0002-8749-6066
Ludwig SachsDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Leonidas D PanosDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Oliver Y UrbanDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Teresa SillerDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Sara Pilgram-PastorUniversity Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Roland GigerDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Martin MüllerDepartment of Emergency Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Franca WagnerUniversity Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInternal carotid artery dissection (ICA-D) frequently leads to ischemic stroke in individuals under 50 years. There is mounting evidence on the role of the styloid process (SP) in ICA-D, particularly SP length and the SP-ICA distance. Despite having clear guidelines on the treatment of SP-related Eagle syndrome and ICA-D, the concept of SP-related ICA-D is relatively new and no therapeutic guidelines exist.

methodsA narrative literature search was performed to identify all articles pertaining to the diagnosis and treatment of ICA-D linked to an ipsilateral elongated SP or short SP-ICA distance. The treatments were evaluated in terms of symptom recurrence after the treatment. As illustrative examples of clinical management, we present an in-house case series of patients with suspected ICA-D related to SP.

resultsTreatment efficacy was assessed, with an in-house case series provided. Seventy-five reports and case studies involving 84 patients were analyzed. Conservative treatments were common (52%) but had a high symptom recurrence rate (33%). It is noteworthy that no patients treated initially with styloidectomy exhibited symptom recurrence.

conclusionIn case of a correctly diagnosed SP-related ICA-D, a styloidectomy may offer a curative option, but more research is needed for clear indications and standardized guidelines to prevent recurrent symptoms or strokes.

Indexed as

Carotid Artery, Internal, DissectionOssification, HeterotopicTemporal BoneFemaleHumansMaleMiddle AgedTreatment OutcomeDissectionInternal carotid arteryStrokeStyloid process

Identifiers

PMID40285871
PMCPMC12357798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.